STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yokLPutative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the acetyltransferase family. (177 aa)    
Predicted Functional Partners:
yokK
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.890
yokJ
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the ability to inhibit growth of cognate toxin YokI upon expression in E.coli. Does not have antitoxin activity on other toxins with the LXG toxin domain.
  
    0.816
yokI
Putative DNA wielding protein; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 449-571) inhibits growth upon expression in E.coli which is neutralized by cognate antitoxin YokJ, but not by antitoxins specific to other toxins with the LXG domain.
  
    0.763
ynaD
Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the acetyltransferase family.
  
    0.760
yokG
Putative transposase fragment; Evidence 7: Gene remnant; putative enzyme; Belongs to the cry6A endotoxin family.
   
    0.622
yopD
Putative conserved hypothetical membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
   
    0.591
yolB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.501
bdbB
Bacteriophage SPbeta thiol-disulfide oxidoreductase; Important but not absolutely essential for the production of the lantibiotic sublancin 168, it may also be required for the stability of other secreted proteins. Not required for competence for DNA uptake; Belongs to the DsbB family. BdbC subfamily.
   
    0.475
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of ribosomal RNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes pre-scRNA (the precursor of the signal recognition particle RNA). Probably also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
    0.461
pksJ
Polyketide synthase of type I; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
  
  
 0.439
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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