STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yokJConserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the ability to inhibit growth of cognate toxin YokI upon expression in E.coli. Does not have antitoxin activity on other toxins with the LXG toxin domain. (165 aa)    
Predicted Functional Partners:
yokI
Putative DNA wielding protein; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 449-571) inhibits growth upon expression in E.coli which is neutralized by cognate antitoxin YokJ, but not by antitoxins specific to other toxins with the LXG domain.
  
    0.927
yokK
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.890
yokL
Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the acetyltransferase family.
  
    0.816
yokH
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.551
yopC
Conserved hypothetical protein; May be the toxic component of a type II toxin-antitoxin (TA) system. Neutralized by its cognate antitoxin YopB. In the C-terminal section; belongs to the MbcT/ParT/Res family.
   
    0.503
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.