STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cotDSpore coat protein (inner); Evidence 1a: Function experimentally demonstrated in the studied strain; cell process. (75 aa)    
Predicted Functional Partners:
gerE
Transcriptional regulator; Involved in the regulation of spore formation. Directs the transcription of several genes that encode structural components of the protein coat that encases the mature spore (CotB, CotC, CotG, CotS, CotV, CotW, CotX, CotY and CotZ). Controls also the cgeAB and cgeCDE operons.
   
  
 0.849
cotC
Spore coat protein (outer); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
   
  
 0.846
cotB
Spore coat protein (outer); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
   
  
 0.842
cotG
Spore morphogenetic protein; May be a morphogenetic protein that is required for the incorporation of protein CotB into the spore coat.
   
  
 0.809
ymaG
Inner spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
   
  
 0.769
cotT
Spore coat protein (inner coat); Inner spore coat protein which seems to play a role in germination.
   
  
 0.765
yaaH
Spore peptidoglycan hydrolase; N-acetylglucosaminidase involved in cortex peptidoglycan degradation during germination. Cleaves only partially degraded spore peptidoglycans. Recognizes muramic acid delta-lactam residues specific to spore peptidoglycans.
      
 0.746
ypsA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0398 family.
  
  
 0.705
ysnD
Inner spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
   
  
 0.698
ytxO
Outer spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
   
  
 0.697
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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