STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ypqAHypothetical protein; Evidence 5: No homology to any previously reported sequences; Belongs to the small heat shock protein (HSP20) family. (139 aa)    
Predicted Functional Partners:
ydgA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.674
clpC
Class III stress response-related ATPase, AAA+ superfamily; Competence gene repressor; required for cell growth at high temperature. Negative regulator of comK expression. May interact with MecA to negatively regulate comK; Belongs to the ClpA/ClpB family. ClpC subfamily.
  
 
 0.668
clpE
ATP-dependent Clp protease (class III stress gene); ATPase essential both for efficient CtsR-dependent gene derepression during heat stress and for rerepression. Together with ClpP, degrades the global regulator CtsR after heat shock. Is also involved in disaggregation of heat-denatured proteins. Has thus a role in overall protein quality control in response to heat stress.
  
 
 0.668
yqfQ
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.642
gerT
Component of the spore coat; Involved in spore germination; probably required at the earliest stage of germination.
  
    0.633
ydgB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.586
dnaK
Molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.577
htpG
Class III heat-shock protein (molecular chaperone); Molecular chaperone. Has ATPase activity.
  
 
 0.572
cotF
Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
   
  
 0.572
ytcA
Putative UDP-glucose dehydrogenase; Catalyzes the conversion of UDP-glucose into UDP-glucuronate, one of the precursors of teichuronic acid.
  
    0.569
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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