STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ypiATPR repeat-containing protein YpiA; Evidence 4: Homologs of previously reported genes of unknown function (423 aa)    
Predicted Functional Partners:
ytsP
L-methionine (r)-s-oxide reductase; Belongs to the free Met sulfoxide reductase family
      
 0.902
ypiB
Conserved hypothetical protein; Belongs to the UPF0302 family
 
     0.843
ytxK
Site-specific dna-methyltransferase (adenine-specific); To type I restriction system adenine methylases
  
    0.763
ypiF
Conserved hypothetical protein; Uncharacterized protein YpiF; Evidence 4: Homologs of previously reported genes of unknown function
 
     0.762
ezrA
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
  
   
 0.712
ypbB
Conserved hypothetical protein; Uncharacterized protein YpbB; Evidence 4: Homologs of previously reported genes of unknown function
 
     0.693
yslB
Conserved hypothetical protein; Uncharacterized protein YslB; Evidence 4: Homologs of previously reported genes of unknown function
  
     0.681
dinG
Damage inducible atp-dependent 3'->5' nuclease; 3'-5' exonuclease
 
  0.655
yjbH
Putative thiol management oxidoreductase component; UPF0413 protein YjbH; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme
  
   
 0.654
aroA
3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvoylshikimate-3-phosphate synthase); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
   
   0.637
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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