STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ypiAConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (423 aa)    
Predicted Functional Partners:
ykuL
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11985717.
 
 
 0.834
ypiB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16847875; Belongs to the UPF0302 family.
 
    0.802
ytxK
Putative nucleic acid methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To type I restriction system adenine methylases.
  
     0.766
ytsP
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the free Met sulfoxide reductase family.
      
 0.755
ypbB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
     0.736
htpG
Class III heat-shock protein (molecular chaperone); Molecular chaperone. Has ATPase activity.
  
 0.723
ypzK
Putative acetyltransferase; Involved in riboflavin biosynthesis.
 
     0.721
ezrA
Negative regulator of FtsZ ring formation; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
  
     0.694
holB
DNA polymerase III delta' subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.
 
   0.678
coiA
Protein involved in establishment of DNA transport in competence; Required for optimal transformation.
  
    0.667
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.