| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cspD | hbs | BSU21930 | BSU22790 | Cold-shock protein, molecular chaperone, RNA-helicase co-factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | 0.641 |
| cspD | hfq | BSU21930 | BSU17340 | Cold-shock protein, molecular chaperone, RNA-helicase co-factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. | Hfq RNA chaperone; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.540 |
| cspD | rplS | BSU21930 | BSU16040 | Cold-shock protein, molecular chaperone, RNA-helicase co-factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; Belongs to the bacterial ribosomal protein bL19 family. | 0.516 |
| cspD | rpsO | BSU21930 | BSU16680 | Cold-shock protein, molecular chaperone, RNA-helicase co-factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. | Ribosomal protein S15 (BS18); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.695 |
| dnaA | hbs | BSU00010 | BSU22790 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression as well as that of other genes. | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | 0.830 |
| dnaA | parB | BSU00010 | BSU40960 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression as well as that of other genes. | Site-specific DNA-binding protein; Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition by Soj. It probably interacts with a specific DNA site and other proteins involved in partitioning and cell division, and antagonizes Soj in response to cell cycle events related to chromosome partitioning. | 0.970 |
| hbs | cspD | BSU22790 | BSU21930 | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | Cold-shock protein, molecular chaperone, RNA-helicase co-factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. | 0.641 |
| hbs | dnaA | BSU22790 | BSU00010 | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression as well as that of other genes. | 0.830 |
| hbs | hfq | BSU22790 | BSU17340 | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | Hfq RNA chaperone; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.783 |
| hbs | lrpC | BSU22790 | BSU04250 | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | Transcriptional regulator (Lrp/AsnC family); Transcriptional regulator with a possible role in regulation of amino acid metabolism. Plays a role in the growth phase transition. | 0.751 |
| hbs | parB | BSU22790 | BSU40960 | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | Site-specific DNA-binding protein; Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition by Soj. It probably interacts with a specific DNA site and other proteins involved in partitioning and cell division, and antagonizes Soj in response to cell cycle events related to chromosome partitioning. | 0.663 |
| hbs | rplL | BSU22790 | BSU01050 | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | Ribosomal protein L12 (BL9); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation. | 0.647 |
| hbs | rplS | BSU22790 | BSU16040 | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; Belongs to the bacterial ribosomal protein bL19 family. | 0.705 |
| hbs | rpsO | BSU22790 | BSU16680 | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | Ribosomal protein S15 (BS18); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.733 |
| hbs | rpsT | BSU22790 | BSU25550 | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | Ribosomal protein S20 (BS20); Binds directly to 16S ribosomal RNA; Belongs to the bacterial ribosomal protein bS20 family. | 0.784 |
| hbs | yfmK | BSU22790 | BSU07440 | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the acetyltransferase family. | 0.882 |
| hfq | cspD | BSU17340 | BSU21930 | Hfq RNA chaperone; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Cold-shock protein, molecular chaperone, RNA-helicase co-factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. | 0.540 |
| hfq | hbs | BSU17340 | BSU22790 | Hfq RNA chaperone; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content. | 0.783 |
| hfq | rplL | BSU17340 | BSU01050 | Hfq RNA chaperone; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribosomal protein L12 (BL9); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation. | 0.500 |
| hfq | rpsO | BSU17340 | BSU16680 | Hfq RNA chaperone; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribosomal protein S15 (BS18); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.607 |
