Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
yphAPutative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (199 aa)    
Predicted Functional Partners:
yphB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.952
ypzH
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.843
engA
GTPase essential for ribosome 50S subunit assembly; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
  
 0.770
ypjA
Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
   
  
 0.746
yddB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.743
yuxJ
Putative exporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
      
 0.716
gpsA
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Involved in the biosynthesis of the sn-glycerol 3-phosphate required for phospholipid synthesis.
       0.654
ypzI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
       0.554
yphE
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
       0.529
yvyG
Putative flagellar protein; May be involved in the assembly, structure, or function of the flagellum. May polymerize to form a filamentous structure that is part of the flagellum.
      
 0.481
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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