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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scpAChromosome condensation and partitioning factor; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves; Belongs to the ScpA family. (251 aa)    
Predicted Functional Partners:
smc
Chromosome condensation and segregation SMC ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.999
spcB
Chromosome condensation and segregation factor; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves; Belongs to the ScpB family.
 
 0.999
parB
Site-specific DNA-binding protein; Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition by Soj. It probably interacts with a specific DNA site and other proteins involved in partitioning and cell division, and antagonizes Soj in response to cell cycle events related to chromosome partitioning.
  
  
 0.943
ypuI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12065423.
  
  
 0.893
cwlP
Lytic transglycosylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; Belongs to the transglycosylase Slt family.
  
 
 0.854
rluB
Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-2633 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
  
 0.824
ypzK
Putative acetyltransferase; Involved in riboflavin biosynthesis.
  
  
 0.809
cmk
Cytidylate kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme.
 
  
 0.792
ypuF
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
  
 0.779
parA
Chromosome partitioning protein; Inhibits the initiation of sporulation, Spo0J antagonizes this inhibition. Soj ultimately inhibits the activation (phosphorylation) of Spo0A; Belongs to the ParA family.
 
  
 0.723
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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