close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ypuFConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (174 aa)    
Predicted Functional Partners:
ypuI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12065423.
  
  
 0.937
ypzJ
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.919
ypzK
Putative acetyltransferase; Involved in riboflavin biosynthesis.
   
  
 0.914
ypzD
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the GerPA/GerPF family.
      
 0.911
spcB
Chromosome condensation and segregation factor; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves; Belongs to the ScpB family.
  
  
 0.872
scpA
Chromosome condensation and partitioning factor; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves; Belongs to the ScpA family.
  
  
 0.779
ywjG
Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
  
     0.743
ribAB
Fused GTP cyclohydrolase II and 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
      
 0.737
kbaA
Inner membrane protein involved in activation of the KinB signaling pathway to sporulation; Involved in the activation of the KinB signaling pathway of sporulation.
  
     0.706
yqzF
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.690
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.