node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fur | ripX | BSU23520 | BSU23510 | Transcriptional regulator for iron transport and metabolism; Iron uptake repressor. Acts on the transcription of ferri- siderophore uptake genes. | Site-specific tyrosine recombinase for chromosome partitioning; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.711 |
fur | yqzK | BSU23520 | BSU23519 | Transcriptional regulator for iron transport and metabolism; Iron uptake repressor. Acts on the transcription of ferri- siderophore uptake genes. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.567 |
gerAB | gerPC | BSU33060 | BSU10700 | Component of the germination receptor GerA; Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor. | 0.482 |
gerAB | yfmI | BSU33060 | BSU07460 | Component of the germination receptor GerA; Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.593 |
gerAB | yqzK | BSU33060 | BSU23519 | Component of the germination receptor GerA; Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.593 |
gerPC | gerAB | BSU10700 | BSU33060 | Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor. | Component of the germination receptor GerA; Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | 0.482 |
gerPC | skfC | BSU10700 | BSU01935 | Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor. | Sporulation killing factor biosynthesis and export; Required for production of the bacteriocin SkfA. | 0.498 |
gerPC | yfmI | BSU10700 | BSU07460 | Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor. | Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.752 |
gerPC | yqzK | BSU10700 | BSU23519 | Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.752 |
mecB | yfmI | BSU22970 | BSU07460 | Regulator of competence and sporulation; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Also involved in Spx degradation by ClpC (By similarity). Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. | Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.645 |
mecB | yqzK | BSU22970 | BSU23519 | Regulator of competence and sporulation; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Also involved in Spx degradation by ClpC (By similarity). Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.645 |
prpC | yfmI | BSU15760 | BSU07460 | Phosphorylated protein phosphatase; Protein phosphatase that dephosphorylates PrkC and EF-G (elongation factor G, fusA). prpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, PrpC's primary role being possibly to counter the action of PrkC. May be involved in sporulation and biofilm formation. Does not seem to be involved in stress response. Dephosphorylates phosphorylated CgsA, EF-Tu and YezB. | Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.573 |
prpC | yqzK | BSU15760 | BSU23519 | Phosphorylated protein phosphatase; Protein phosphatase that dephosphorylates PrkC and EF-G (elongation factor G, fusA). prpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, PrpC's primary role being possibly to counter the action of PrkC. May be involved in sporulation and biofilm formation. Does not seem to be involved in stress response. Dephosphorylates phosphorylated CgsA, EF-Tu and YezB. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.573 |
ripX | fur | BSU23510 | BSU23520 | Site-specific tyrosine recombinase for chromosome partitioning; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | Transcriptional regulator for iron transport and metabolism; Iron uptake repressor. Acts on the transcription of ferri- siderophore uptake genes. | 0.711 |
ripX | yqzK | BSU23510 | BSU23519 | Site-specific tyrosine recombinase for chromosome partitioning; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.803 |
skfC | gerPC | BSU01935 | BSU10700 | Sporulation killing factor biosynthesis and export; Required for production of the bacteriocin SkfA. | Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor. | 0.498 |
skfC | spmA | BSU01935 | BSU23180 | Sporulation killing factor biosynthesis and export; Required for production of the bacteriocin SkfA. | Spore maturation protein; Involved in spore core dehydration; might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex peptidoglycan structure. | 0.402 |
skfC | yfmI | BSU01935 | BSU07460 | Sporulation killing factor biosynthesis and export; Required for production of the bacteriocin SkfA. | Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.858 |
skfC | yqzK | BSU01935 | BSU23519 | Sporulation killing factor biosynthesis and export; Required for production of the bacteriocin SkfA. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.849 |
spmA | skfC | BSU23180 | BSU01935 | Spore maturation protein; Involved in spore core dehydration; might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex peptidoglycan structure. | Sporulation killing factor biosynthesis and export; Required for production of the bacteriocin SkfA. | 0.402 |