STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yqxKConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To M.jannaschii MJ0043 N-terminal region. (387 aa)    
Predicted Functional Partners:
pcrA
ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair.
 
    0.870
yjcD
Putative ATP-dependent DNA helicase; May be involved in the generation of recombinogenic substrates for the subsequent action of RecA.
      0.865
nudF
ADP-ribose pyrophosphatase; Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process (By similarity).
  
    0.859
sspF
Small acid-soluble spore protein (alpha/beta-type SASP); May play some important role in either sporulation or the dormant spore.
  
    0.623
mciZ
Cell division factor; Blocks Z-ring formation in the mother cell during sporulation by inhibiting the polymerization of FtsZ. Binds to the minus end of FtsZ and functions as a filament-capping protein. At high concentrations, is capable of both capping and sequestration of FtsZ. Decreases the GTPase activity of FtsZ.
       0.553
yqkF
NADPH-dependent aldo-keto reductase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
       0.507
yheD
Spore coat associated protein; Involved in sporulation.
  
     0.494
ykoP
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
 
     0.471
yjcA
Sporulation-specific protein; Involved in sporulation.
  
     0.464
fosB
Metallothiol transferase; Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.
  
     0.457
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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