node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
abrB | bslA | BSU00370 | BSU31080 | Abrb family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription | Biofilm hydrophobic layer component; Involved in biofilm formation Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm The layer is stable and capable of resistance to high mechanical force compression . Required for complex colony architecture . May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix | 0.788 |
abrB | epsA | BSU00370 | BSU34370 | Abrb family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription | Uncharacterized protein YveK; Evidence 2b: Function of strongly homologous gene; Product type r : regulator | 0.881 |
abrB | epsO | BSU00370 | BSU34220 | Abrb family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription | Putative pyruvyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles | 0.410 |
abrB | sinI | BSU00370 | BSU24600 | Abrb family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription | Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE | 0.902 |
abrB | sinR | BSU00370 | BSU24610 | Abrb family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription | Xre family transcriptional regulator, master regulator for biofilm formation; Negative as well as positive regulator of alternate developmental processes that are induced at the end of vegetative growth in response to nutrient depletion. Binds to the alkaline protease (aprE) gene at two sites. Also acts as a repressor of the key sporulation gene spo0A. Negatively regulates transcription of the eps operon, which is responsible for the biosynthesis of an exopolysaccharide involved in biofilm formation; therefore it could govern the transition between a state in which bacteria swim or swa [...] | 0.932 |
abrB | sipW | BSU00370 | BSU24630 | Abrb family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription | Type i signal peptidase; Required for the cleavage of the signal sequence of TasA and TapA, which are involved in biofilm formation | 0.901 |
abrB | slrR | BSU00370 | BSU34380 | Abrb family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription | Hth-type transcriptional regulator, biofilm formation regulator; Represses sigma(D)-dependent flagellar genes and activate the eps and yqxM operons. Repressor activity is regulated by SlrA. Controls the initiation of biofilm formation | 0.884 |
abrB | spo0A | BSU00370 | BSU24220 | Abrb family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription | Two-component system, response regulator, stage 0 sporulation protein a; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) | 0.988 |
abrB | tapA | BSU00370 | BSU24640 | Abrb family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription | Lipoprotein for biofilm formation; Required for biofilm formation Required for the proper anchoring and polymerization of TasA amyloid fibers at the cell surface . Is also a minor component of TasA fibers | 0.901 |
bslA | abrB | BSU31080 | BSU00370 | Biofilm hydrophobic layer component; Involved in biofilm formation Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm The layer is stable and capable of resistance to high mechanical force compression . Required for complex colony architecture . May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix | Abrb family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription | 0.788 |
bslA | epsA | BSU31080 | BSU34370 | Biofilm hydrophobic layer component; Involved in biofilm formation Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm The layer is stable and capable of resistance to high mechanical force compression . Required for complex colony architecture . May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix | Uncharacterized protein YveK; Evidence 2b: Function of strongly homologous gene; Product type r : regulator | 0.920 |
bslA | epsO | BSU31080 | BSU34220 | Biofilm hydrophobic layer component; Involved in biofilm formation Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm The layer is stable and capable of resistance to high mechanical force compression . Required for complex colony architecture . May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix | Putative pyruvyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles | 0.645 |
bslA | sinI | BSU31080 | BSU24600 | Biofilm hydrophobic layer component; Involved in biofilm formation Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm The layer is stable and capable of resistance to high mechanical force compression . Required for complex colony architecture . May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix | Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE | 0.809 |
bslA | sinR | BSU31080 | BSU24610 | Biofilm hydrophobic layer component; Involved in biofilm formation Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm The layer is stable and capable of resistance to high mechanical force compression . Required for complex colony architecture . May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix | Xre family transcriptional regulator, master regulator for biofilm formation; Negative as well as positive regulator of alternate developmental processes that are induced at the end of vegetative growth in response to nutrient depletion. Binds to the alkaline protease (aprE) gene at two sites. Also acts as a repressor of the key sporulation gene spo0A. Negatively regulates transcription of the eps operon, which is responsible for the biosynthesis of an exopolysaccharide involved in biofilm formation; therefore it could govern the transition between a state in which bacteria swim or swa [...] | 0.901 |
bslA | sipW | BSU31080 | BSU24630 | Biofilm hydrophobic layer component; Involved in biofilm formation Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm The layer is stable and capable of resistance to high mechanical force compression . Required for complex colony architecture . May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix | Type i signal peptidase; Required for the cleavage of the signal sequence of TasA and TapA, which are involved in biofilm formation | 0.910 |
bslA | slrR | BSU31080 | BSU34380 | Biofilm hydrophobic layer component; Involved in biofilm formation Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm The layer is stable and capable of resistance to high mechanical force compression . Required for complex colony architecture . May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix | Hth-type transcriptional regulator, biofilm formation regulator; Represses sigma(D)-dependent flagellar genes and activate the eps and yqxM operons. Repressor activity is regulated by SlrA. Controls the initiation of biofilm formation | 0.712 |
bslA | spo0A | BSU31080 | BSU24220 | Biofilm hydrophobic layer component; Involved in biofilm formation Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm The layer is stable and capable of resistance to high mechanical force compression . Required for complex colony architecture . May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix | Two-component system, response regulator, stage 0 sporulation protein a; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) | 0.880 |
bslA | tapA | BSU31080 | BSU24640 | Biofilm hydrophobic layer component; Involved in biofilm formation Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm The layer is stable and capable of resistance to high mechanical force compression . Required for complex colony architecture . May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix | Lipoprotein for biofilm formation; Required for biofilm formation Required for the proper anchoring and polymerization of TasA amyloid fibers at the cell surface . Is also a minor component of TasA fibers | 0.930 |
epsA | abrB | BSU34370 | BSU00370 | Uncharacterized protein YveK; Evidence 2b: Function of strongly homologous gene; Product type r : regulator | Abrb family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription | 0.881 |
epsA | bslA | BSU34370 | BSU31080 | Uncharacterized protein YveK; Evidence 2b: Function of strongly homologous gene; Product type r : regulator | Biofilm hydrophobic layer component; Involved in biofilm formation Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm The layer is stable and capable of resistance to high mechanical force compression . Required for complex colony architecture . May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix | 0.920 |