STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comGGComponent of the DNA transport platform; Required for transformation and DNA binding. (124 aa)    
Predicted Functional Partners:
comGF
Component of the DNA transport platform; Required for transformation and DNA binding.
  
  
 0.998
comGE
Component of the DNA transport platform; Required for transformation and DNA binding.
  
  
 0.997
comGC
Pilin-like component of the DNA transport membrane platform; Required for transformation and DNA binding. Belongs to the ComGC family.
  
  
 0.996
comGD
Membrane component of the DNA transport platform; Required for transformation and DNA binding.
  
  
 0.994
comGB
Membrane platform component of the DNA transport machinery; Required for transformation and DNA binding. Belongs to the GSP F family.
  
  
 0.990
comGA
Membrane associated ATPase for DNA competence; Required for uptake of DNA by competent cells.
  
  
 0.990
yqzE
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
  
 0.952
comC
Membrane protease and transmethylase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue; Belongs to the peptidase A24 family.
   
  
 0.948
comEA
Membrane bound high-affinity DNA-binding receptor; Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect.
   
  
 0.927
comFA
Helicase competence protein; Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel. Belongs to the helicase family.
   
  
 0.920
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.