STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yqfL[pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation (270 aa)    
Predicted Functional Partners:
ccpN
Deor family transcriptional regulator, catabolite repression regulator; Transcription repressor that binds to the promoter of gapB and pckA genes, preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes
 
   
 0.993
yqxD
Conserved hypothetical protein; Belongs to the UPF0178 family
     
 0.846
glyQ
Glycyl-trna synthetase (alpha subunit); Glycine--tRNA ligase alpha subunit; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme
 
     0.714
glyS
Glycyl-trna synthetase (beta subunit); Glycine--tRNA ligase beta subunit; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme
 
     0.712
rpsU
Small subunit ribosomal protein s21; Belongs to the bacterial ribosomal protein bS21 family
     
 0.712
dnaG
Dna primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
     
 0.675
yabM
Polysaccharide transporter, pst family; Uncharacterized membrane protein YabM; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter
      
 0.647
ywmB
Conserved hypothetical protein; Uncharacterized protein YwmB; Evidence 4: Homologs of previously reported genes of unknown function
      
 0.586
yqzE
Conserved hypothetical protein; Uncharacterized protein YqzE; Evidence 4: Homologs of previously reported genes of unknown function
      
 0.580
recO
Dna double strand break repair and homologous recombination factor; Plays a role in DNA double-stranded break repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecR. Is recruited to repair centers, foci that are the site of double-strand break(s) after RecN and before RecF; may actively recruit RecF
       0.529
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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