node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gerAA | gpr | BSU33050 | BSU25540 | Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | 0.902 |
gerAA | spo0A | BSU33050 | BSU24220 | Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box). | 0.752 |
gerAA | spoIIAB | BSU33050 | BSU23460 | Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.764 |
gerAA | spoIIP | BSU33050 | BSU25530 | Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Spore autolysin (stage II sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.422 |
gerAA | spoIVA | BSU33050 | BSU22800 | Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Morphogenetic stage IV sporulation protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Its ATP hydrolysis is required for proper assembly of the spore coat. Forms a basement layer around the outside surface of the forespore and self-assembles irreversibly into higher order structures by binding and hydrolyzing ATP thus creating a durable and stable platform upon which thereafter morphogenesis of the coat can take place. Required for proper localization of spore coat protein CotE and sporulation-specific proteins including SpoVM. | 0.787 |
gerAA | spoVAC | BSU33050 | BSU23420 | Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Stage V sporulation protein AC; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.925 |
gerAA | spoVAD | BSU33050 | BSU23410 | Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Stage V sporulation protein AD; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.949 |
gerAA | spoVAEB | BSU33050 | BSU23402 | Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Spore germinant protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.865 |
gerAA | spoVT | BSU33050 | BSU00560 | Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Transcriptional regulator; Transcriptional factor that regulates positively or negatively the expression of a large number of forespore-specific sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development. SpoVT levels during spore formation have a major impact on the germination and the resistance of the resultant spores. To B.subtilis AbrB and Abh. | 0.774 |
gerAA | yyaC | BSU33050 | BSU40950 | Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.663 |
gpr | gerAA | BSU25540 | BSU33050 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence. | 0.902 |
gpr | spo0A | BSU25540 | BSU24220 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box). | 0.824 |
gpr | spoIIAB | BSU25540 | BSU23460 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.818 |
gpr | spoIIP | BSU25540 | BSU25530 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Spore autolysin (stage II sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.962 |
gpr | spoIVA | BSU25540 | BSU22800 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Morphogenetic stage IV sporulation protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Its ATP hydrolysis is required for proper assembly of the spore coat. Forms a basement layer around the outside surface of the forespore and self-assembles irreversibly into higher order structures by binding and hydrolyzing ATP thus creating a durable and stable platform upon which thereafter morphogenesis of the coat can take place. Required for proper localization of spore coat protein CotE and sporulation-specific proteins including SpoVM. | 0.893 |
gpr | spoVAC | BSU25540 | BSU23420 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Stage V sporulation protein AC; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.970 |
gpr | spoVAD | BSU25540 | BSU23410 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Stage V sporulation protein AD; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.975 |
gpr | spoVAEB | BSU25540 | BSU23402 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Spore germinant protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.894 |
gpr | spoVT | BSU25540 | BSU00560 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Transcriptional regulator; Transcriptional factor that regulates positively or negatively the expression of a large number of forespore-specific sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development. SpoVT levels during spore formation have a major impact on the germination and the resistance of the resultant spores. To B.subtilis AbrB and Abh. | 0.820 |
gpr | yyaC | BSU25540 | BSU40950 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.903 |