STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yqxIHypothetical protein; Evidence 5: No homology to any previously reported sequences. (159 aa)    
Predicted Functional Partners:
yqxJ
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
  
    0.968
yonX
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.756
nupN
Lipoprotein involved in guanosine transport; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein.
   
  
 0.684
yxaI
Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
   
  
 0.684
yybN
Conserved hypothetical protein; Evidence 7: Gene remnant.
   
  
 0.584
yhzC
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
      
 0.572
ywqI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.501
cwlA
N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
       0.466
cssS
Two-component sensor histidine kinase; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htrA. Could detect misfolded proteins at the membrane-cell wall interface and then activate CssR by phosphorylation.
      
 0.426
htrA
Membrane bound serine protease Do, quality control protease (heat-shock protein); Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (Probable); Belongs to the peptidase S1C family.
      
 0.420
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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