STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yrkSRNA polymerase sporulation-specific sigma-K factor precursor (Sigma-27) (C-terminal fragment); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor. (54 aa)    
Predicted Functional Partners:
ycxB
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
      
 0.858
ydeK
Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
      
 0.858
ydjC
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.858
yraK
Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the AB hydrolase superfamily.
      
 0.858
ywhH
Putative RNA-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
      
 0.850
yurS
Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 9852018.
      
 0.846
yyaJ
Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
      
 0.758
yurT
Putative methylglyoxalase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glyoxalase I family.
      
 0.753
yybP
Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
      
 0.572
slpS
Phosphosulfolactate synthase; Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL) (By similarity). Is probably involved in the biosynthesis of L-sulfolactate, which is a major constituent of sporulating cells and mature spores. Belongs to the phosphosulfolactate synthase family.
   
  
 0.495
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.