STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yrkQTwo-component sensor histidine kinase [YrkP]; Member of the two-component regulatory system YrkQ/YrkP. Probably activates YrkP by phosphorylation. (432 aa)    
Predicted Functional Partners:
yrkP
Two-component response regulator [YrkQ]; Member of the two-component regulatory system YrkQ/YrkP.
 
 
 0.940
yrkO
Putative integral inner membrane protein; Involved in transport.
 
    0.768
psiE
Phosphate starvation inducible protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; membrane component.
  
    0.733
yxdJ
Two-component response regulator [YxdK]; Probable member of the two-component regulatory system YxdK/YxdJ. Positively regulates the expression of the yxdLMyxeA operon by direct interaction with its promoter region. Could also indirectly regulate the expression of the dlt operon.
 
 
 0.450
yvrH
Two-component response regulator YvrH involved in cell wall processes [YvrG]; Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA-yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX-rsiX), and negatively regulates the lytABC operon.
 
 
 0.444
ykoG
Two-component response regulator [YkoH]; Probable member of the two-component regulatory system YkoH/YkoG.
 
 
 0.429
ycbL
Two-component response regulator [YcbM]; Member of the two-component regulatory system YcbM/YcbL.
 
 
 0.427
yvcP
Two-component response regulator [YvcQ]; Member of the two-component regulatory system YvcQ/YvcP.
 
 
 0.427
yclJ
Two-component response regulator [YclK]; Could be member of the two-component regulatory system YclK/YclJ.
 
 
 0.423
azlD
Branched-chain amino acid transporter; Involved in branched-chain amino acid transport; Belongs to the AzlD/HI_1737/HP1330 family.
  
     0.409
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.