STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yrkDPutative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (63 aa)    
Predicted Functional Partners:
mtlR
Transcriptional regulator; Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol.
   
    0.746
yrkJ
Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
 
  
 0.637
yrkE
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
 
    0.615
yrkH
Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
 
  
 0.587
yrkF
Putative rhodanese-related sulfur transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the sulfur carrier protein TusA family.
 
    0.584
copA
Copper transporter ATPase; Involved in copper export.
  
  
 0.548
ywzB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
     0.492
ygaE
Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
  
     0.482
yvcD
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
     0.477
yrkI
Putative sulfur-carrier protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier; Belongs to the sulfur carrier protein TusA family.
 
    0.450
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.