STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yrdPPutative oxidoreductase; Involved in potassium and divalent cation transport. Enhances the transport activity of the cation/potassium transporter CzcD. (345 aa)    
Predicted Functional Partners:
yugO
Putative potassium channel protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
      
 0.919
czcD
Potassium/proton-divalent cation antiporter; Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions.
  
    0.902
ktrC
Potassium uptake protein; Catalytic subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress.
      
 0.807
atpA
ATP synthase (subunit alpha, component F1); Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit; Belongs to the ATPase alpha/beta chains family.
   
   0.732
yvnB
Putative exported phosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
     
 0.712
copB
copper(I)-transporting ATPase; Couples the hydrolysis of ATP with the transport of cadmium, zinc and cobalt out of the cell. Does not seem to transport copper.
  
  
 0.684
mstX
Atypical membrane-integrating protein (Mistic protein); Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer.
      
 0.681
atpG
ATP synthase (subunit gamma, component F1); Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
   
   0.664
rplQ
Ribosomal protein L17 (BL15); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
   
   0.612
ktrA
Potassium uptake protein; Catalytic subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress.
      
 0.592
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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