STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brnQBranched-chain amino acid transport system carrier protein brnq; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force (440 aa)    
Predicted Functional Partners:
bcaP
Branched-chain amino acid transporter; Belongs to the amino acid-polyamine-organocation (APC) superfamily
     
 0.899
yrdK
Hypothetical protein; Uncharacterized protein YrdK; Evidence 5: No homology to any previously reported sequences
     
 0.871
yuiF
Putative amino acid transporter YuiF; Evidence 2b: Function of strongly homologous gene; Product type t: transporter
  
   
 0.846
azlB
Transcriptional regulator (lrp/asnc family); Transcriptional repressor of the azlBCD operon involved in branched-chain amino acid transport
     
 0.668
codY
Gtp-sensing transcriptional pleiotropic repressor cody; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase and sporulation. It is a GTP- binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
      
 0.661
yvbW
Amino acid transporter, aat family; May participate in leucine metabolism. May transport leucine or a compound related to leucine metabolism
      
 0.644
azlC
Branched-chain amino acid transport protein azlc; Involved in branched-chain amino acid transport
     
 0.600
azlD
Branched-chain amino acid transport protein azld; Involved in branched-chain amino acid transport
     
 0.574
ywiE
Cardiolipin synthase a/b; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity). May have a role in the heat shock response since the level of the transcript of ywiE increases after a heat shock
      
 0.483
atoB
Succinyl-CoA:3-ketoacid coenzyme A transferase subunit B; Belongs to the 3-oxoacid CoA-transferase subunit B family
      
 0.449
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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