Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yrdFPutative ribonuclease inhibitor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor. (91 aa)    
Predicted Functional Partners:
cypA
Cytochrome P450; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
     
 0.829
ydfE
Putative flavoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
  
   
 0.711
yvdB
Putative anion transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
      
 0.694
ydfF
Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
      
 0.639
yvcT
Putative 2-hydroxyacid dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
      
 0.635
azlC
Branched-chain amino acid transporter; Involved in branched-chain amino acid transport; Belongs to the AzlC family.
 
    0.490
rhgH
Rhamnogalacturonan hydrolase; Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D-galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D-glucuronic acid at the non-reducing terminus, although the active pockets of YesR and UGL are very similar. Belongs to the glycosyl hydrolase 105 family.
   
  
 0.487
azlD
Branched-chain amino acid transporter; Involved in branched-chain amino acid transport; Belongs to the AzlD/HI_1737/HP1330 family.
 
    0.482
yvdA
Putative carbonic anhydrase; Reversible hydration of carbon dioxide.
   
  
 0.453
azlB
Transcriptional regulator (Lrp/AsnC family); Transcriptional repressor of the azlBCD operon involved in branched-chain amino acid transport.
  
    0.433
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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