STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yrdAConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DinB family. (167 aa)    
Predicted Functional Partners:
yisT
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DinB family.
 
  
 0.946
yizA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DinB family.
      
 0.908
ykkA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
  
 0.908
yxeO
Putative ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Responsible for energy coupling to the transport system (Probable).
      
 0.907
yusE
Putative thiol-disulfide oxidoreductase with thioredoxin domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
  
 0.904
yxdK
Two-component sensor histidine kinase [YxdJ]; Probable member of the two-component regulatory system YxdK/YxdJ. May activate YxdJ in response to the antibacterial protein LL-37.
      
 0.880
nupO
Guanosine ABC transporter (ATP-binding protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter; Belongs to the ABC transporter superfamily.
   
  
 0.871
yuaE
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
   
 0.790
yjoA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
  
 0.775
yisL
Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
   
  
 0.716
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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