| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| rpoB | rpoC | BSU01070 | BSU01080 | RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase (beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoB | sigV | BSU01070 | BSU27120 | RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | 0.598 |
| rpoB | sigX | BSU01070 | BSU23100 | RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase ECF(extracytoplasmic function)-type sigma factor sigma(X); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism; Belongs to the sigma-70 factor family. ECF subfamily. | 0.532 |
| rpoB | sigY | BSU01070 | BSU38700 | RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase ECF (extracytoplasmic function)-type sigma factor (sigma-Y); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of the sigY-yxlCDEFG operon upon nitrogen starvation. Also positively regulates ybgB. | 0.532 |
| rpoB | sigZ | BSU01070 | BSU26840 | RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma-Z); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.532 |
| rpoC | rpoB | BSU01080 | BSU01070 | RNA polymerase (beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoC | sigV | BSU01080 | BSU27120 | RNA polymerase (beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | 0.582 |
| rpoC | sigX | BSU01080 | BSU23100 | RNA polymerase (beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase ECF(extracytoplasmic function)-type sigma factor sigma(X); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism; Belongs to the sigma-70 factor family. ECF subfamily. | 0.597 |
| rpoC | sigY | BSU01080 | BSU38700 | RNA polymerase (beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase ECF (extracytoplasmic function)-type sigma factor (sigma-Y); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of the sigY-yxlCDEFG operon upon nitrogen starvation. Also positively regulates ybgB. | 0.582 |
| rpoC | sigZ | BSU01080 | BSU26840 | RNA polymerase (beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma-Z); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.582 |
| rsiW | sigV | BSU01740 | BSU27120 | anti-sigma(W) factor; The anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-W (SigW). Holds SigW, its cognate ECF sigma factor, in an inactive form until released by regulated intramembrane proteolysis (RIP). SigW and RsiW mediate cell response to cell wall stress. RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, PrsW) , then within the membrane itself (site-2 protease, S2P [...] | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | 0.666 |
| rsiW | sigX | BSU01740 | BSU23100 | anti-sigma(W) factor; The anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-W (SigW). Holds SigW, its cognate ECF sigma factor, in an inactive form until released by regulated intramembrane proteolysis (RIP). SigW and RsiW mediate cell response to cell wall stress. RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, PrsW) , then within the membrane itself (site-2 protease, S2P [...] | RNA polymerase ECF(extracytoplasmic function)-type sigma factor sigma(X); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism; Belongs to the sigma-70 factor family. ECF subfamily. | 0.708 |
| rsiW | sigY | BSU01740 | BSU38700 | anti-sigma(W) factor; The anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-W (SigW). Holds SigW, its cognate ECF sigma factor, in an inactive form until released by regulated intramembrane proteolysis (RIP). SigW and RsiW mediate cell response to cell wall stress. RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, PrsW) , then within the membrane itself (site-2 protease, S2P [...] | RNA polymerase ECF (extracytoplasmic function)-type sigma factor (sigma-Y); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of the sigY-yxlCDEFG operon upon nitrogen starvation. Also positively regulates ybgB. | 0.653 |
| rsiW | sigZ | BSU01740 | BSU26840 | anti-sigma(W) factor; The anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-W (SigW). Holds SigW, its cognate ECF sigma factor, in an inactive form until released by regulated intramembrane proteolysis (RIP). SigW and RsiW mediate cell response to cell wall stress. RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, PrsW) , then within the membrane itself (site-2 protease, S2P [...] | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma-Z); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.587 |
| sigV | rpoB | BSU27120 | BSU01070 | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.598 |
| sigV | rpoC | BSU27120 | BSU01080 | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | RNA polymerase (beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.582 |
| sigV | rsiW | BSU27120 | BSU01740 | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | anti-sigma(W) factor; The anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-W (SigW). Holds SigW, its cognate ECF sigma factor, in an inactive form until released by regulated intramembrane proteolysis (RIP). SigW and RsiW mediate cell response to cell wall stress. RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, PrsW) , then within the membrane itself (site-2 protease, S2P [...] | 0.666 |
| sigV | sigX | BSU27120 | BSU23100 | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | RNA polymerase ECF(extracytoplasmic function)-type sigma factor sigma(X); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism; Belongs to the sigma-70 factor family. ECF subfamily. | 0.484 |
| sigV | sigY | BSU27120 | BSU38700 | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | RNA polymerase ECF (extracytoplasmic function)-type sigma factor (sigma-Y); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of the sigY-yxlCDEFG operon upon nitrogen starvation. Also positively regulates ybgB. | 0.963 |
| sigV | sigZ | BSU27120 | BSU26840 | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma-Z); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.963 |