STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsiVanti-sigma(V) factor; Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction. (285 aa)    
Predicted Functional Partners:
sigV
RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.996
oatA
Peptidoglycan O-acetyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme.
  
  
 0.894
yrhK
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
  
 0.783
bmrR
Transcriptional regulator (MerR family); Activates transcription of the bmr gene in response to structurally dissimilar drugs. Binds rhodamine as an inducer.
  
    0.450
yrhO
Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
  
    0.449
bltR
Transcriptional regulator; Activates transcription of the blt gene in response to structurally dissimilar drugs.
  
    0.446
yraL
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
 
     0.427
ydfL
Putative transcriptional regulator of efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
  
    0.411
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.