| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dltA | oatA | BSU38500 | BSU27140 | D-alanine:D-alanyl-carrier protein ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP [...] | Peptidoglycan O-acetyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | 0.875 |
| dltA | sigV | BSU38500 | BSU27120 | D-alanine:D-alanyl-carrier protein ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP [...] | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | 0.751 |
| dltA | yrhK | BSU38500 | BSU27150 | D-alanine:D-alanyl-carrier protein ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP [...] | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.480 |
| oatA | dltA | BSU27140 | BSU38500 | Peptidoglycan O-acetyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | D-alanine:D-alanyl-carrier protein ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP [...] | 0.875 |
| oatA | rsiV | BSU27140 | BSU27130 | Peptidoglycan O-acetyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | anti-sigma(V) factor; Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction. | 0.894 |
| oatA | sigV | BSU27140 | BSU27120 | Peptidoglycan O-acetyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | 0.968 |
| oatA | yrhK | BSU27140 | BSU27150 | Peptidoglycan O-acetyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.902 |
| rsiV | oatA | BSU27130 | BSU27140 | anti-sigma(V) factor; Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction. | Peptidoglycan O-acetyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | 0.894 |
| rsiV | sigV | BSU27130 | BSU27120 | anti-sigma(V) factor; Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction. | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | 0.996 |
| rsiV | yrhK | BSU27130 | BSU27150 | anti-sigma(V) factor; Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.783 |
| sigV | dltA | BSU27120 | BSU38500 | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | D-alanine:D-alanyl-carrier protein ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP [...] | 0.751 |
| sigV | oatA | BSU27120 | BSU27140 | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | Peptidoglycan O-acetyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | 0.968 |
| sigV | rsiV | BSU27120 | BSU27130 | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | anti-sigma(V) factor; Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction. | 0.996 |
| sigV | yrhK | BSU27120 | BSU27150 | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.840 |
| yfhO | yrhK | BSU08610 | BSU27150 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.412 |
| yrhK | dltA | BSU27150 | BSU38500 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | D-alanine:D-alanyl-carrier protein ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP [...] | 0.480 |
| yrhK | oatA | BSU27150 | BSU27140 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Peptidoglycan O-acetyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme. | 0.902 |
| yrhK | rsiV | BSU27150 | BSU27130 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | anti-sigma(V) factor; Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction. | 0.783 |
| yrhK | sigV | BSU27150 | BSU27120 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily. | 0.840 |
| yrhK | yfhO | BSU27150 | BSU08610 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.412 |