node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acsA | ppnKB | BSU29680 | BSU29540 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.596 |
acsA | yrhF | BSU29680 | BSU27210 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.487 |
fdhD | yjgC | BSU36710 | BSU12160 | Putative subunit of an respiration oxidoreductase; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH (By similarity); Belongs to the FdhD family. | Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.928 |
fdhD | yjgD | BSU36710 | BSU12170 | Putative subunit of an respiration oxidoreductase; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH (By similarity); Belongs to the FdhD family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.764 |
fdhD | yrhD | BSU36710 | BSU27230 | Putative subunit of an respiration oxidoreductase; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH (By similarity); Belongs to the FdhD family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10913079; To A.fulgidus AF1717. | 0.943 |
fdhD | yrhE | BSU36710 | BSU27220 | Putative subunit of an respiration oxidoreductase; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH (By similarity); Belongs to the FdhD family. | Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.987 |
fdhD | yrhF | BSU36710 | BSU27210 | Putative subunit of an respiration oxidoreductase; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH (By similarity); Belongs to the FdhD family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.637 |
fdhD | yrhG | BSU36710 | BSU27200 | Putative subunit of an respiration oxidoreductase; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH (By similarity); Belongs to the FdhD family. | Putative formate/nitrite transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.513 |
ppnKB | acsA | BSU29540 | BSU29680 | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate. | 0.596 |
ppnKB | yrhF | BSU29540 | BSU27210 | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.764 |
yjgC | fdhD | BSU12160 | BSU36710 | Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | Putative subunit of an respiration oxidoreductase; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH (By similarity); Belongs to the FdhD family. | 0.928 |
yjgC | yjgD | BSU12160 | BSU12170 | Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.998 |
yjgC | yrhD | BSU12160 | BSU27230 | Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10913079; To A.fulgidus AF1717. | 0.962 |
yjgC | yrhE | BSU12160 | BSU27220 | Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.903 |
yjgC | yrhF | BSU12160 | BSU27210 | Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.636 |
yjgC | yrhG | BSU12160 | BSU27200 | Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | Putative formate/nitrite transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.493 |
yjgD | fdhD | BSU12170 | BSU36710 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative subunit of an respiration oxidoreductase; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH (By similarity); Belongs to the FdhD family. | 0.764 |
yjgD | yjgC | BSU12170 | BSU12160 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.998 |
yjgD | yrhD | BSU12170 | BSU27230 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10913079; To A.fulgidus AF1717. | 0.474 |
yjgD | yrhE | BSU12170 | BSU27220 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.909 |