node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alaS | polA | BSU27410 | BSU29090 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | 0.477 |
alaS | yrrI | BSU27410 | BSU27420 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.480 |
alaS | yrzL | BSU27410 | BSU27400 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0297 family. | 0.722 |
glnH | glnQ | BSU27440 | BSU27430 | Glutamine ABC transporter (glutamine-binding lipoprotein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport; Belongs to the bacterial solute-binding protein 3 family. | Glutamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for energy coupling to the transport system (By similarity). | 0.999 |
glnH | yrrI | BSU27440 | BSU27420 | Glutamine ABC transporter (glutamine-binding lipoprotein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport; Belongs to the bacterial solute-binding protein 3 family. | Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.492 |
glnQ | glnH | BSU27430 | BSU27440 | Glutamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for energy coupling to the transport system (By similarity). | Glutamine ABC transporter (glutamine-binding lipoprotein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport; Belongs to the bacterial solute-binding protein 3 family. | 0.999 |
glnQ | yrrI | BSU27430 | BSU27420 | Glutamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for energy coupling to the transport system (By similarity). | Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.524 |
mleN | yfkE | BSU23560 | BSU07920 | malate-H+/Na+-lactate antiporter; Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport, in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force; Belongs to the NhaC Na(+)/H(+) (TC 2.A.35) antiporter family. | Putative H+/Ca2+ antiporter; Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Does not transport sodium or potassium. Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/proton exchanger (CAX) subfamily. | 0.681 |
mleN | yrrI | BSU23560 | BSU27420 | malate-H+/Na+-lactate antiporter; Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport, in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force; Belongs to the NhaC Na(+)/H(+) (TC 2.A.35) antiporter family. | Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.632 |
polA | alaS | BSU29090 | BSU27410 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.477 |
polA | recF | BSU29090 | BSU00040 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | DNA repair and genetic recombination factor; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. Is recruited to repair centers, foci that are the site of double- strand DNA break(s) after RecN and RecO; recruitment may depend on RecO. | 0.626 |
polA | recG | BSU29090 | BSU15870 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | Branch migrating ATP-dependent DNA helicase involved in DNA recombination and repair; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily. | 0.808 |
polA | yrrI | BSU29090 | BSU27420 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.475 |
recF | polA | BSU00040 | BSU29090 | DNA repair and genetic recombination factor; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. Is recruited to repair centers, foci that are the site of double- strand DNA break(s) after RecN and RecO; recruitment may depend on RecO. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | 0.626 |
recF | recG | BSU00040 | BSU15870 | DNA repair and genetic recombination factor; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. Is recruited to repair centers, foci that are the site of double- strand DNA break(s) after RecN and RecO; recruitment may depend on RecO. | Branch migrating ATP-dependent DNA helicase involved in DNA recombination and repair; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily. | 0.969 |
recF | yrrI | BSU00040 | BSU27420 | DNA repair and genetic recombination factor; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. Is recruited to repair centers, foci that are the site of double- strand DNA break(s) after RecN and RecO; recruitment may depend on RecO. | Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.491 |
recG | polA | BSU15870 | BSU29090 | Branch migrating ATP-dependent DNA helicase involved in DNA recombination and repair; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | 0.808 |
recG | recF | BSU15870 | BSU00040 | Branch migrating ATP-dependent DNA helicase involved in DNA recombination and repair; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily. | DNA repair and genetic recombination factor; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. Is recruited to repair centers, foci that are the site of double- strand DNA break(s) after RecN and RecO; recruitment may depend on RecO. | 0.969 |
recG | yrrI | BSU15870 | BSU27420 | Branch migrating ATP-dependent DNA helicase involved in DNA recombination and repair; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily. | Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.418 |
yfkE | mleN | BSU07920 | BSU23560 | Putative H+/Ca2+ antiporter; Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Does not transport sodium or potassium. Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/proton exchanger (CAX) subfamily. | malate-H+/Na+-lactate antiporter; Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport, in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force; Belongs to the NhaC Na(+)/H(+) (TC 2.A.35) antiporter family. | 0.681 |