STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoVBPutative putative translocase with flippase function for teichoic acid synthesis; Involved, directly or indirectly, in spore cortex biosynthesis. Affects only indirectly the expression of late sporulation genes. (518 aa)    
Predicted Functional Partners:
spoVE
Factor for spore cortex peptidoglycan synthesis (stage V sporulation); May play an essential role not only during sporulation, but also during vegetative growth; Belongs to the SEDS family. SpoVE subfamily.
  
  
 0.939
spoVD
Penicillin-binding protein; Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell.
  
  
 0.924
spoIIP
Spore autolysin (stage II sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
  
  
 0.848
cotE
Morphogenic spore protein; Morphogenic protein required for the assembly of the outer coat of the endospore. Is also a regulatory protein for the expression of cotA, cotB, cotC, cotH and other genes encoding spore outer coat proteins.
  
  
 0.816
ylbJ
Putative factor required for spore cortex formation; Required for spore cortex formation.
  
  
 0.808
spoVID
Morphogenetic spore protein (stage VI sporulation); Required for assembly of a normal spore coat. May be a component of the innermost layer of the spore coat that aids in its adherence to the prespore.
  
  
 0.784
spoIIE
SpoIIAA-phosphate serine phosphatase; Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates SpoIIAA by dephosphorylation.
  
  
 0.774
spoIID
Autolysin required for complete dissolution of the asymmetric septum (stage II sporulation); May act at the level of sigma-G activity or its stability. SpoIID is probably required for engulfment.
  
  
 0.763
yabP
Spore protein involved in the shaping of the spore coat; Required for sporulation.
 
  
 0.762
ydcC
Putative lipoprotein; required for efficient sporulation.
  
    0.756
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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