STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yrbDPutative sodium/proton-dependent alanine carrier protein YrbD; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter (484 aa)    
Predicted Functional Partners:
yocR
Uncharacterized sodium-dependent transporter YocR; Putative sodium-dependent transporter
 
  
 0.761
pucR
Purine catabolism regulatory protein; Activates the expression of pucFG, pucH, pucI, pucJKLM and guaD, while it represses pucABCDE and its own expression
      
 0.748
yodF
Uncharacterized symporter YodF; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family
   
  
 0.747
pucK
Uric acid permease PucK; Uptake of uric acid
     
 0.744
ycsF
UPF0271 protein YcsF; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; Belongs to the UPF0271 (lamB) family
   
  
 0.735
yvgT
UPF0126 membrane protein YvgT; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component
   
  
 0.691
yocS
Uncharacterized sodium-dependent transporter YocS; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter
     
 0.684
ywrD
Glutathione hydrolase-like YwrD proenzyme; Overexpressed protein with an N-terminal His tag has been reported not to hydolyze glutathione; it is not clear if the construct is processed to 2 subunits; Belongs to the gamma-glutamyltransferase family
      
 0.666
ydaB
Putative acyl--CoA ligase YdaB; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the ATP-dependent AMP-binding enzyme family
      
 0.661
citA
Citrate synthase 1; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect; Belongs to the citrate synthase family
   
  
 0.632
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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