node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bkdR | ylmC | BSU24100 | BSU15360 | Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12429060. | 0.681 |
bkdR | ylxY | BSU24100 | BSU16700 | Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Putative sugar deacetylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the polysaccharide deacetylase family. | 0.709 |
bkdR | ylzA | BSU24100 | BSU15670 | Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Conserved hypothetical protein; Regulates the biosynthesis of the extracellular matrix and the biofilm formation. Activates the transcription of the matrix biosynthesis operons eps and tapA-sipW- tasA. Also activates expression of the opuA operon, involved in osmoprotection. Acts by binding specifically to the promoter region of the target genes. Acts in parallel to the pathway that governs SinR derepression. Required for endosporulation. | 0.914 |
bkdR | ytaF | BSU24100 | BSU29070 | Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. | 0.890 |
bkdR | ytxC | BSU24100 | BSU28960 | Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.845 |
coaE | mutM | BSU29060 | BSU29080 | Dephosphocoenzyme A kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | formamidopyrimidine-DNA glycosidase; Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo- dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions (By similarity). Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 8-oxo-dGTP. Has AP (apurinic/apyrimidi [...] | 0.990 |
coaE | ytaF | BSU29060 | BSU29070 | Dephosphocoenzyme A kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. | 0.939 |
mutM | coaE | BSU29080 | BSU29060 | formamidopyrimidine-DNA glycosidase; Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo- dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions (By similarity). Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 8-oxo-dGTP. Has AP (apurinic/apyrimidi [...] | Dephosphocoenzyme A kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.990 |
mutM | ytaF | BSU29080 | BSU29070 | formamidopyrimidine-DNA glycosidase; Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo- dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions (By similarity). Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 8-oxo-dGTP. Has AP (apurinic/apyrimidi [...] | Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. | 0.810 |
spoVFA | yabG | BSU16730 | BSU00430 | Spore dipicolinate synthase subunit A; Together with DpaB, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA), which constitutes up to 10% of the dry weight of the spore. | Sporulation-specific protease; Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross-linking of coat proteins like GerQ. | 0.618 |
spoVFA | yabP | BSU16730 | BSU00600 | Spore dipicolinate synthase subunit A; Together with DpaB, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA), which constitutes up to 10% of the dry weight of the spore. | Spore protein involved in the shaping of the spore coat; Required for sporulation. | 0.579 |
spoVFA | ylmC | BSU16730 | BSU15360 | Spore dipicolinate synthase subunit A; Together with DpaB, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA), which constitutes up to 10% of the dry weight of the spore. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12429060. | 0.554 |
spoVFA | ylxY | BSU16730 | BSU16700 | Spore dipicolinate synthase subunit A; Together with DpaB, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA), which constitutes up to 10% of the dry weight of the spore. | Putative sugar deacetylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the polysaccharide deacetylase family. | 0.472 |
spoVFA | ytaF | BSU16730 | BSU29070 | Spore dipicolinate synthase subunit A; Together with DpaB, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA), which constitutes up to 10% of the dry weight of the spore. | Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. | 0.723 |
yabG | spoVFA | BSU00430 | BSU16730 | Sporulation-specific protease; Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross-linking of coat proteins like GerQ. | Spore dipicolinate synthase subunit A; Together with DpaB, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA), which constitutes up to 10% of the dry weight of the spore. | 0.618 |
yabG | yabP | BSU00430 | BSU00600 | Sporulation-specific protease; Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross-linking of coat proteins like GerQ. | Spore protein involved in the shaping of the spore coat; Required for sporulation. | 0.612 |
yabG | ytaF | BSU00430 | BSU29070 | Sporulation-specific protease; Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross-linking of coat proteins like GerQ. | Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. | 0.802 |
yabG | ytxC | BSU00430 | BSU28960 | Sporulation-specific protease; Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross-linking of coat proteins like GerQ. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.554 |
yabP | spoVFA | BSU00600 | BSU16730 | Spore protein involved in the shaping of the spore coat; Required for sporulation. | Spore dipicolinate synthase subunit A; Together with DpaB, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA), which constitutes up to 10% of the dry weight of the spore. | 0.579 |
yabP | yabG | BSU00600 | BSU00430 | Spore protein involved in the shaping of the spore coat; Required for sporulation. | Sporulation-specific protease; Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross-linking of coat proteins like GerQ. | 0.612 |