| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gpr | sleB | BSU25540 | BSU22930 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. | 0.777 |
| gpr | spoIIID | BSU25540 | BSU36420 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | 0.785 |
| gpr | spoIVB | BSU25540 | BSU24230 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter. | 0.813 |
| gpr | ylmC | BSU25540 | BSU15360 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12429060. | 0.784 |
| gpr | ymxH | BSU25540 | BSU16720 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the YlmC/YmxH family. | 0.679 |
| gpr | ypeB | BSU25540 | BSU22920 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Spore membrane component; Required for spore cortex hydrolysis during germination. Appears to be required for either expression, localization, activation or function of SleB. | 0.548 |
| gpr | ytfI | BSU25540 | BSU29510 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.603 |
| gpr | ytfJ | BSU25540 | BSU29500 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.819 |
| gpr | yunB | BSU25540 | BSU32350 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Putative protein involved in spore formation; Required for sporulation. | 0.713 |
| sleB | gpr | BSU22930 | BSU25540 | Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | 0.777 |
| sleB | spoIIID | BSU22930 | BSU36420 | Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | 0.787 |
| sleB | spoIVB | BSU22930 | BSU24230 | Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. | Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter. | 0.712 |
| sleB | spoVID | BSU22930 | BSU28110 | Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. | Morphogenetic spore protein (stage VI sporulation); Required for assembly of a normal spore coat. May be a component of the innermost layer of the spore coat that aids in its adherence to the prespore. | 0.484 |
| sleB | ypeB | BSU22930 | BSU22920 | Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. | Spore membrane component; Required for spore cortex hydrolysis during germination. Appears to be required for either expression, localization, activation or function of SleB. | 0.999 |
| sleB | ytfJ | BSU22930 | BSU29500 | Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.842 |
| sleB | yunB | BSU22930 | BSU32350 | Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. | Putative protein involved in spore formation; Required for sporulation. | 0.588 |
| spoIIID | gpr | BSU36420 | BSU25540 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | 0.785 |
| spoIIID | sleB | BSU36420 | BSU22930 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. | 0.787 |
| spoIIID | spoIVB | BSU36420 | BSU24230 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter. | 0.929 |
| spoIIID | spoVID | BSU36420 | BSU28110 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Morphogenetic spore protein (stage VI sporulation); Required for assembly of a normal spore coat. May be a component of the innermost layer of the spore coat that aids in its adherence to the prespore. | 0.809 |
