| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gpr | sigG | BSU25540 | BSU15330 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | 0.781 |
| gpr | sleB | BSU25540 | BSU22930 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. | 0.752 |
| gpr | spoIIID | BSU25540 | BSU36420 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | 0.782 |
| gpr | spoIVB | BSU25540 | BSU24230 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter. | 0.813 |
| gpr | ylbJ | BSU25540 | BSU15030 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Putative factor required for spore cortex formation; Required for spore cortex formation. | 0.775 |
| gpr | ylmC | BSU25540 | BSU15360 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12429060. | 0.770 |
| gpr | ymxH | BSU25540 | BSU16720 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the YlmC/YmxH family. | 0.654 |
| gpr | ytfI | BSU25540 | BSU29510 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.607 |
| gpr | ytfJ | BSU25540 | BSU29500 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.814 |
| gpr | yunB | BSU25540 | BSU32350 | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | Putative protein involved in spore formation; Required for sporulation. | 0.713 |
| sigG | gpr | BSU15330 | BSU25540 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | 0.781 |
| sigG | sleB | BSU15330 | BSU22930 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. | 0.487 |
| sigG | spoIIID | BSU15330 | BSU36420 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | 0.948 |
| sigG | spoIVB | BSU15330 | BSU24230 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter. | 0.879 |
| sigG | ylbJ | BSU15330 | BSU15030 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Putative factor required for spore cortex formation; Required for spore cortex formation. | 0.760 |
| sigG | ylmC | BSU15330 | BSU15360 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12429060. | 0.854 |
| sigG | ymxH | BSU15330 | BSU16720 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the YlmC/YmxH family. | 0.717 |
| sigG | ytfJ | BSU15330 | BSU29500 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.777 |
| sigG | yunB | BSU15330 | BSU32350 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Putative protein involved in spore formation; Required for sporulation. | 0.690 |
| sleB | gpr | BSU22930 | BSU25540 | Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components. | Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination. | 0.752 |