node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cysE | iscSB | BSU00930 | BSU29590 | Serine o-acetyltransferase; Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS) | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | 0.770 |
cysE | sufU | BSU00930 | BSU32680 | Serine o-acetyltransferase; Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS) | Nitrogen fixation protein nifu and related proteins; Its function is controversial. Has been generally assumed to be an iron-sulfur cluster assembly scaffold protein but more recent evidence suggest it is a sulfurtransferase rather than a scaffold assembly protein . Has been shown to bind low levels of a labile, air- sensitive Fe-S cluster; this can be assembled under anaerobic conditions from FeCl(3) and Li(2)S. Has been shown to be able to transfer this Fe-S cluster to an acceptor protein. Stimulates the cysteine desulfurase activity of SufS, for which it acts as a second substrate. [...] | 0.486 |
gcvPB | iscSB | BSU24550 | BSU29590 | Glycine decarboxylase (subunit 2) (glycine cleavage system protein p); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity) | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | 0.598 |
iscSA | iscSB | BSU27510 | BSU29590 | Cysteine desulfurase involved in trna thiolation; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | 0.820 |
iscSA | moeB | BSU27510 | BSU14270 | Cysteine desulfurase involved in trna thiolation; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Molybdopterin biosynthesis adenylyltransferase; Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD | 0.888 |
iscSA | nifS | BSU27510 | BSU27880 | Cysteine desulfurase involved in trna thiolation; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Putative desulfurase involved in iron-sulfur clusters for nad biosynthesis; Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). Seems to be required for NAD biosynthesis | 0.829 |
iscSA | sufU | BSU27510 | BSU32680 | Cysteine desulfurase involved in trna thiolation; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Nitrogen fixation protein nifu and related proteins; Its function is controversial. Has been generally assumed to be an iron-sulfur cluster assembly scaffold protein but more recent evidence suggest it is a sulfurtransferase rather than a scaffold assembly protein . Has been shown to bind low levels of a labile, air- sensitive Fe-S cluster; this can be assembled under anaerobic conditions from FeCl(3) and Li(2)S. Has been shown to be able to transfer this Fe-S cluster to an acceptor protein. Stimulates the cysteine desulfurase activity of SufS, for which it acts as a second substrate. [...] | 0.976 |
iscSA | thiI | BSU27510 | BSU29580 | Cysteine desulfurase involved in trna thiolation; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Putative persulfide atp pyrophosphatase involved in thiamine biosynthesis and trna modification; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS | 0.982 |
iscSA | yrkF | BSU27510 | BSU26530 | Cysteine desulfurase involved in trna thiolation; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Putative rhodanese-related sulfur transferase; Belongs to the sulfur carrier protein TusA family | 0.997 |
iscSB | cysE | BSU29590 | BSU00930 | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Serine o-acetyltransferase; Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS) | 0.770 |
iscSB | gcvPB | BSU29590 | BSU24550 | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Glycine decarboxylase (subunit 2) (glycine cleavage system protein p); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity) | 0.598 |
iscSB | iscSA | BSU29590 | BSU27510 | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Cysteine desulfurase involved in trna thiolation; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | 0.820 |
iscSB | moeA | BSU29590 | BSU14280 | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Molybdene to molybdopterin ligation enzyme; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP | 0.638 |
iscSB | moeB | BSU29590 | BSU14270 | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Molybdopterin biosynthesis adenylyltransferase; Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD | 0.888 |
iscSB | nifS | BSU29590 | BSU27880 | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Putative desulfurase involved in iron-sulfur clusters for nad biosynthesis; Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). Seems to be required for NAD biosynthesis | 0.835 |
iscSB | sspA | BSU29590 | BSU29570 | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Small acid-soluble spore protein a (major alpha-type sasp); SASP are bound to spore DNA. They are double-stranded DNA- binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light | 0.613 |
iscSB | sufU | BSU29590 | BSU32680 | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Nitrogen fixation protein nifu and related proteins; Its function is controversial. Has been generally assumed to be an iron-sulfur cluster assembly scaffold protein but more recent evidence suggest it is a sulfurtransferase rather than a scaffold assembly protein . Has been shown to bind low levels of a labile, air- sensitive Fe-S cluster; this can be assembled under anaerobic conditions from FeCl(3) and Li(2)S. Has been shown to be able to transfer this Fe-S cluster to an acceptor protein. Stimulates the cysteine desulfurase activity of SufS, for which it acts as a second substrate. [...] | 0.979 |
iscSB | thiI | BSU29590 | BSU29580 | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Putative persulfide atp pyrophosphatase involved in thiamine biosynthesis and trna modification; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS | 0.995 |
iscSB | yrkF | BSU29590 | BSU26530 | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | Putative rhodanese-related sulfur transferase; Belongs to the sulfur carrier protein TusA family | 0.976 |
moeA | iscSB | BSU14280 | BSU29590 | Molybdene to molybdopterin ligation enzyme; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP | Cysteine desulfurase iscs 2; Catalyzes the removal of elemental sulfur from cysteine to produce alanine | 0.638 |