| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acsA | acuA | BSU29680 | BSU29690 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate. | Protein acetyltransferase; Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue. | 0.998 |
| acsA | acuB | BSU29680 | BSU29700 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate. | Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. | 0.750 |
| acsA | acuC | BSU29680 | BSU29710 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate. | Protein deacetylase; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source; Belongs to the histone deacetylase family. | 0.980 |
| acsA | guaA | BSU29680 | BSU06360 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.754 |
| acsA | srtN | BSU29680 | BSU09650 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate. | Sirtuin NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.927 |
| acuA | acsA | BSU29690 | BSU29680 | Protein acetyltransferase; Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate. | 0.998 |
| acuA | acuB | BSU29690 | BSU29700 | Protein acetyltransferase; Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue. | Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. | 0.981 |
| acuA | acuC | BSU29690 | BSU29710 | Protein acetyltransferase; Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue. | Protein deacetylase; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source; Belongs to the histone deacetylase family. | 0.998 |
| acuA | srtN | BSU29690 | BSU09650 | Protein acetyltransferase; Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue. | Sirtuin NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.928 |
| acuA | yrbE | BSU29690 | BSU27770 | Protein acetyltransferase; Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue. | Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the Gfo/Idh/MocA family. | 0.541 |
| acuB | acsA | BSU29700 | BSU29680 | Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate. | 0.750 |
| acuB | acuA | BSU29700 | BSU29690 | Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. | Protein acetyltransferase; Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue. | 0.981 |
| acuB | acuC | BSU29700 | BSU29710 | Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. | Protein deacetylase; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source; Belongs to the histone deacetylase family. | 0.988 |
| acuB | dnaH | BSU29700 | BSU00330 | Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. | Subunit of the DNA replication complex; Involved in initiation control of chromosome replication. | 0.605 |
| acuB | galT | BSU29700 | BSU38190 | Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. | Galactose-1-phosphate uridyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | 0.451 |
| acuB | guaA | BSU29700 | BSU06360 | Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.691 |
| acuB | rbsR | BSU29700 | BSU35910 | Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. | Transcriptional regulator (LacI family); Transcriptional repressor for the ribose rbsDACBK operon. | 0.454 |
| acuB | rppG | BSU29700 | BSU30630 | Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. | Nucleoside and RNA triphosphate phosphohydrolase; Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo- dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions (By similarity). Functions, in conjunction with MutT, to protect vegetatively growing cells from DNA- damaging agents such as H(2)O(2) or t-BHP (t-butylhydroperoxide). The 2 proteins do not however protect spores. According to phosphohydrola [...] | 0.586 |
| acuB | srtN | BSU29700 | BSU09650 | Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. | Sirtuin NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.474 |
| acuB | yrbE | BSU29700 | BSU27770 | Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source. | Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the Gfo/Idh/MocA family. | 0.476 |
