node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bshA | bshBA | BSU22460 | BSU22470 | Malate glycosyltransferase for bacillithiol synthesis; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway, the formation of N-acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Malate N-acetylglucosamine N-acetyl hydrolase; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family. | 0.998 |
bshA | bshC | BSU22460 | BSU15120 | Malate glycosyltransferase for bacillithiol synthesis; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway, the formation of N-acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Malate glucosamine cysteine ligase; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH. | 0.995 |
bshA | bshR | BSU22460 | BSU21860 | Malate glycosyltransferase for bacillithiol synthesis; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway, the formation of N-acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Protein disulfide isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the UPF0403 family. | 0.941 |
bshA | ypdA | BSU22460 | BSU22950 | Malate glycosyltransferase for bacillithiol synthesis; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway, the formation of N-acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Putative FAD-dependent disulfide oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.958 |
bshA | yqiW | BSU22460 | BSU23990 | Malate glycosyltransferase for bacillithiol synthesis; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway, the formation of N-acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0403 family. | 0.924 |
bshA | ytxJ | BSU22460 | BSU29760 | Malate glycosyltransferase for bacillithiol synthesis; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway, the formation of N-acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232. | 0.896 |
bshBA | bshA | BSU22470 | BSU22460 | Malate N-acetylglucosamine N-acetyl hydrolase; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family. | Malate glycosyltransferase for bacillithiol synthesis; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway, the formation of N-acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | 0.998 |
bshBA | bshC | BSU22470 | BSU15120 | Malate N-acetylglucosamine N-acetyl hydrolase; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family. | Malate glucosamine cysteine ligase; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH. | 0.982 |
bshBA | bshR | BSU22470 | BSU21860 | Malate N-acetylglucosamine N-acetyl hydrolase; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family. | Protein disulfide isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the UPF0403 family. | 0.873 |
bshBA | ypdA | BSU22470 | BSU22950 | Malate N-acetylglucosamine N-acetyl hydrolase; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family. | Putative FAD-dependent disulfide oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.657 |
bshBA | yqiW | BSU22470 | BSU23990 | Malate N-acetylglucosamine N-acetyl hydrolase; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0403 family. | 0.706 |
bshBA | ytxJ | BSU22470 | BSU29760 | Malate N-acetylglucosamine N-acetyl hydrolase; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232. | 0.806 |
bshC | bshA | BSU15120 | BSU22460 | Malate glucosamine cysteine ligase; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH. | Malate glycosyltransferase for bacillithiol synthesis; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway, the formation of N-acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | 0.995 |
bshC | bshBA | BSU15120 | BSU22470 | Malate glucosamine cysteine ligase; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH. | Malate N-acetylglucosamine N-acetyl hydrolase; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family. | 0.982 |
bshC | bshR | BSU15120 | BSU21860 | Malate glucosamine cysteine ligase; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH. | Protein disulfide isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the UPF0403 family. | 0.964 |
bshC | ypdA | BSU15120 | BSU22950 | Malate glucosamine cysteine ligase; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH. | Putative FAD-dependent disulfide oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.976 |
bshC | yqiW | BSU15120 | BSU23990 | Malate glucosamine cysteine ligase; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0403 family. | 0.941 |
bshC | ytxJ | BSU15120 | BSU29760 | Malate glucosamine cysteine ligase; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232. | 0.912 |
bshR | bshA | BSU21860 | BSU22460 | Protein disulfide isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the UPF0403 family. | Malate glycosyltransferase for bacillithiol synthesis; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway, the formation of N-acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. | 0.941 |
bshR | bshBA | BSU21860 | BSU22470 | Protein disulfide isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the UPF0403 family. | Malate N-acetylglucosamine N-acetyl hydrolase; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family. | 0.873 |