Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ytrBABC transporter (ATP-binding protein); Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation. (292 aa)    
Predicted Functional Partners:
ytrC
ABC transporter, permease component; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
  
  
 0.994
ytrD
ABC transporter, permease component; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
  
  
 0.992
ytrF
Metabolite permease; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
  
  
 0.991
ytrA
Transcriptional regulator (GntR family); Negatively regulates ABC transporter complex ytrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
 
  
 0.989
ytrE
ABC transporter (ATP-binding protein); Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
 
  
0.977
skfE
Sporulation killing factor biosynthesis and export; Probably part of the ABC transporter SkfEF involved in the export of the bacteriocin SKF. Probably responsible for energy coupling to the transport system.
 
    
0.904
yhcF
Putative transcriptional regulator (GntR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
 
    0.872
ecfAB
Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
   
0.744
ydfI
Two-component response regulator [YdfH]; Member of the two-component regulatory system YdfH/YdfI. Regulates the transcription of ydfJ by binding to its promoter region.
  
  
 0.701
BSU30466
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
       0.668
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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