node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fur | mntC | BSU23520 | BSU30750 | Transcriptional regulator for iron transport and metabolism; Iron uptake repressor. Acts on the transcription of ferri- siderophore uptake genes. | Manganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the ABC-3 integral membrane protein family. | 0.757 |
fur | zur | BSU23520 | BSU25100 | Transcriptional regulator for iron transport and metabolism; Iron uptake repressor. Acts on the transcription of ferri- siderophore uptake genes. | Transcriptional regulator (Fur family); Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes. Required for the zinc-specific repression of two operons implicated in zinc uptake, yciC and ycdHIyceA. Also represses the expression of rpmE2, the gene for ribosomal protein L31B, which is expressed only after the end of exponential growth. | 0.453 |
mntA | mntB | BSU30770 | BSU30760 | Manganese ABC transporter (manganese binding lipoprotein); Probably part of the ABC transporter complex MntABCD involved in manganese import. | Manganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport system. | 0.999 |
mntA | mntC | BSU30770 | BSU30750 | Manganese ABC transporter (manganese binding lipoprotein); Probably part of the ABC transporter complex MntABCD involved in manganese import. | Manganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the ABC-3 integral membrane protein family. | 0.999 |
mntA | mntD | BSU30770 | BSU30740 | Manganese ABC transporter (manganese binding lipoprotein); Probably part of the ABC transporter complex MntABCD involved in manganese import. | Manganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the ABC-3 integral membrane protein family. | 0.999 |
mntA | mntH | BSU30770 | BSU04360 | Manganese ABC transporter (manganese binding lipoprotein); Probably part of the ABC transporter complex MntABCD involved in manganese import. | Manganese transporter; H(+)-stimulated, divalent metal cation uptake system. Involved in manganese uptake. Can probably also transport cadmium, cobalt, copper and zinc, but not iron. May be the predominant transporter of manganese during logarithmic phase growth. | 0.915 |
mntA | mntR | BSU30770 | BSU24520 | Manganese ABC transporter (manganese binding lipoprotein); Probably part of the ABC transporter complex MntABCD involved in manganese import. | Transcriptional regulator (DtxR family); Central regulator of manganese homeostasis that regulates the expression of both manganese uptake and efflux systems. In the presence of high levels of manganese, it mediates repression of the manganese uptake systems MntH and MntABCD and activation of the efflux systems MneP and MneS. Binds with high affinity to the regulatory regions of its target genes. The manganese concentration required for activation of efflux is higher than that for repression of uptake ; Belongs to the DtxR/MntR family. | 0.818 |
mntA | znuA | BSU30770 | BSU02850 | Manganese ABC transporter (manganese binding lipoprotein); Probably part of the ABC transporter complex MntABCD involved in manganese import. | Zn(II)-binding lipoprotein; Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). ZnuABC-mediated zinc transport is required for comF expression and competence development. | 0.519 |
mntA | znuC | BSU30770 | BSU02860 | Manganese ABC transporter (manganese binding lipoprotein); Probably part of the ABC transporter complex MntABCD involved in manganese import. | Zn(II) transporter (ATP-binding protein); Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). Responsible for energy coupling to the transport system (By similarity). ZnuABC-mediated zinc transport is required for comF expression and competence development. | 0.948 |
mntB | mntA | BSU30760 | BSU30770 | Manganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport system. | Manganese ABC transporter (manganese binding lipoprotein); Probably part of the ABC transporter complex MntABCD involved in manganese import. | 0.999 |
mntB | mntC | BSU30760 | BSU30750 | Manganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport system. | Manganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the ABC-3 integral membrane protein family. | 0.999 |
mntB | mntD | BSU30760 | BSU30740 | Manganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport system. | Manganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the ABC-3 integral membrane protein family. | 0.999 |
mntB | mntH | BSU30760 | BSU04360 | Manganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport system. | Manganese transporter; H(+)-stimulated, divalent metal cation uptake system. Involved in manganese uptake. Can probably also transport cadmium, cobalt, copper and zinc, but not iron. May be the predominant transporter of manganese during logarithmic phase growth. | 0.956 |
mntB | mntR | BSU30760 | BSU24520 | Manganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport system. | Transcriptional regulator (DtxR family); Central regulator of manganese homeostasis that regulates the expression of both manganese uptake and efflux systems. In the presence of high levels of manganese, it mediates repression of the manganese uptake systems MntH and MntABCD and activation of the efflux systems MneP and MneS. Binds with high affinity to the regulatory regions of its target genes. The manganese concentration required for activation of efflux is higher than that for repression of uptake ; Belongs to the DtxR/MntR family. | 0.816 |
mntB | znuA | BSU30760 | BSU02850 | Manganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport system. | Zn(II)-binding lipoprotein; Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). ZnuABC-mediated zinc transport is required for comF expression and competence development. | 0.950 |
mntB | znuC | BSU30760 | BSU02860 | Manganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport system. | Zn(II) transporter (ATP-binding protein); Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). Responsible for energy coupling to the transport system (By similarity). ZnuABC-mediated zinc transport is required for comF expression and competence development. | 0.654 |
mntB | zur | BSU30760 | BSU25100 | Manganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport system. | Transcriptional regulator (Fur family); Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes. Required for the zinc-specific repression of two operons implicated in zinc uptake, yciC and ycdHIyceA. Also represses the expression of rpmE2, the gene for ribosomal protein L31B, which is expressed only after the end of exponential growth. | 0.447 |
mntC | fur | BSU30750 | BSU23520 | Manganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the ABC-3 integral membrane protein family. | Transcriptional regulator for iron transport and metabolism; Iron uptake repressor. Acts on the transcription of ferri- siderophore uptake genes. | 0.757 |
mntC | mntA | BSU30750 | BSU30770 | Manganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the ABC-3 integral membrane protein family. | Manganese ABC transporter (manganese binding lipoprotein); Probably part of the ABC transporter complex MntABCD involved in manganese import. | 0.999 |
mntC | mntB | BSU30750 | BSU30760 | Manganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the ABC-3 integral membrane protein family. | Manganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport system. | 0.999 |