STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cotISpore coat kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. (357 aa)    
Predicted Functional Partners:
cotSA
Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
  
 0.995
ytcC
Putative glucosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
  
 0.983
yvdP
Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
   
  
 0.941
ytcB
Putative UDP-glucose epimerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
  
 0.919
cotS
Spore coat protein; Seems to be required for the assembly of the CotSA protein in spores.
 
  
0.886
ytcA
Putative UDP-glucose dehydrogenase; Catalyzes the conversion of UDP-glucose into UDP-glucuronate, one of the precursors of teichuronic acid.
 
  
 0.880
ysxE
Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
  
  
 0.841
cotB
Spore coat protein (outer); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
   
  
 0.815
cotU
Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
   
  
 0.755
cgeB
Protein involved in maturation of the outermost layer of the spore; May be involved in maturation of the outermost layer of the spore.
   
  
 0.748
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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