STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yugSPutative membrane protein involved in divalent ion export; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (429 aa)    
Predicted Functional Partners:
yugP
Putative metal-dependent protease/peptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
  
    0.736
mgtE
Magnesium transporter; Acts as a magnesium transporter.
     
 0.701
ywfM
Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
      
 0.578
yhaU
Transporter involved in K+ efflux; Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Can also mediate rubidium/proton antiport, but has no permeability for sodium or lithium ions. In the absence of KhtT, does not have antiport activity, but can catalyze potassium efflux. Involved in protection of the cell from methylglyoxal, a toxic by-product of glycolysis, via activation by S-lactoyl-BSH of the antiporter activity, leading to cytoplasmic acidification and methylglyoxal resistance ; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transpo [...]
  
  
 0.544
yuzI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Product type f: factor.
       0.533
yugT
Putative oligo-1,6-glucosidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glycosyl hydrolase 13 family.
  
    0.511
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.424
yugO
Putative potassium channel protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
    0.412
mstX
Atypical membrane-integrating protein (Mistic protein); Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer.
       0.401
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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