Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yuzIConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Product type f: factor. (87 aa)    
Predicted Functional Partners:
yugP
Putative metal-dependent protease/peptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
       0.642
yuzM
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.603
yizC
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.578
mstX
Atypical membrane-integrating protein (Mistic protein); Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer.
  
    0.578
yugO
Putative potassium channel protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
    0.577
spoVAEB
Spore germinant protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
   
    0.542
yugS
Putative membrane protein involved in divalent ion export; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
       0.533
gpr
Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination.
   
    0.523
yozT
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
   
    0.471
yugT
Putative oligo-1,6-glucosidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glycosyl hydrolase 13 family.
  
    0.409
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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