STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yugJPutative NADH-dependent butanol dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (387 aa)    
Predicted Functional Partners:
yqjM
NADPH-dependent flavin oxidoreductase; Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes; Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
  
  
 0.857
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
    0.851
nfrAA
FMN-containing NADPH-linked nitro/flavin reductase; Reduces FMNH(2) to FMN, with NADPH as reductant. It also reduces nitroaromatic compounds, quinones and azo dyes.
  
  
 0.844
ywnB
Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
  
  
 0.802
yhfK
Putative epimerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.777
yfmJ
Putative oxidoreductase; Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds; Belongs to the NADP-dependent oxidoreductase L4BD family.
  
  
 0.750
yqiG
Putative NADH-dependent flavin oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
  
  
 0.738
yqkF
NADPH-dependent aldo-keto reductase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
  
  
 0.723
yugK
Putative NADH-dependent butanol dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
 
   
0.657
trxA
Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
   
  
 0.650
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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