STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kapBFactor required for KinB signal transduction and activation of the phosphorelay to sporulation; May play a role in the activation or the expression of KinB. (128 aa)    
Predicted Functional Partners:
kinB
Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the KinB activity.
  
  
 0.950
kbaA
Inner membrane protein involved in activation of the KinB signaling pathway to sporulation; Involved in the activation of the KinB signaling pathway of sporulation.
  
  
 0.800
ycbM
Two-component sensor histidine kinase [YcbL]; Member of the two-component regulatory system YcbM/YcbL. Probably activates YcbL by phosphorylation.
   
  
 0.757
ylmA
Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
  
 0.687
patB
Promiscuous cystathionine beta-lyase / cysteine desulfhydrase; Catalyzes the transformation of cystathionine to homocysteine. Also exhibits cysteine desulfhydrase activity in vitro, producing sulfide from cysteine; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily.
  
  
 0.668
ypgR
Putative lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
  
     0.651
yeaA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
   
 0.629
yvlB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
   
 0.623
ypuF
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
     0.579
ymcC
Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
  
   
 0.562
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.