node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
kapD | rph | BSU31470 | BSU28370 | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. Plays a role in the secondary pathway of 23S rRNA 3' end maturation. | 0.527 |
kapD | rplX | BSU31470 | BSU01270 | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | Ribosomal protein L24 (BL23); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. Has also been isolated as a basic, heat-shock stable DNA- binding protein from the B.subtilis nucleoid. It binds cooperatively to double-stranded supercoiled DNA which it further compacts into complexes 15-17 nm in diameter. Overexpression of the protein disrupts nucleoid segregation and positioning. | 0.450 |
kapD | yhaM | BSU31470 | BSU09930 | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | 3'-5' exonuclease; Shows a 3'-5' exoribonuclease activity as well as single- stranded DNA 3'-5'exonuclease activity. Plays a role in the secondary pathway of 23S rRNA 3' end maturation; Belongs to the YhaM family. | 0.528 |
kapD | yheC | BSU31470 | BSU09780 | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | Spore coat associated protein, similar to YheD; Involved in sporulation; Belongs to the YheC/YheD family. | 0.643 |
kapD | yheD | BSU31470 | BSU09770 | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | Spore coat associated protein; Involved in sporulation. | 0.469 |
kapD | yprB | BSU31470 | BSU22210 | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | Putative nucleic acid binding enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.665 |
kapD | yueB | BSU31470 | BSU31860 | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | 0.542 |
kapD | yuxJ | BSU31470 | BSU31480 | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | Putative exporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. | 0.525 |
kapD | yvcP | BSU31470 | BSU34720 | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | Two-component response regulator [YvcQ]; Member of the two-component regulatory system YvcQ/YvcP. | 0.919 |
kapD | yvcR | BSU31470 | BSU34700 | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily. | 0.483 |
rph | kapD | BSU28370 | BSU31470 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. Plays a role in the secondary pathway of 23S rRNA 3' end maturation. | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | 0.527 |
rph | yhaM | BSU28370 | BSU09930 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. Plays a role in the secondary pathway of 23S rRNA 3' end maturation. | 3'-5' exonuclease; Shows a 3'-5' exoribonuclease activity as well as single- stranded DNA 3'-5'exonuclease activity. Plays a role in the secondary pathway of 23S rRNA 3' end maturation; Belongs to the YhaM family. | 0.921 |
rplX | kapD | BSU01270 | BSU31470 | Ribosomal protein L24 (BL23); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. Has also been isolated as a basic, heat-shock stable DNA- binding protein from the B.subtilis nucleoid. It binds cooperatively to double-stranded supercoiled DNA which it further compacts into complexes 15-17 nm in diameter. Overexpression of the protein disrupts nucleoid segregation and positioning. | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | 0.450 |
yhaM | kapD | BSU09930 | BSU31470 | 3'-5' exonuclease; Shows a 3'-5' exoribonuclease activity as well as single- stranded DNA 3'-5'exonuclease activity. Plays a role in the secondary pathway of 23S rRNA 3' end maturation; Belongs to the YhaM family. | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | 0.528 |
yhaM | rph | BSU09930 | BSU28370 | 3'-5' exonuclease; Shows a 3'-5' exoribonuclease activity as well as single- stranded DNA 3'-5'exonuclease activity. Plays a role in the secondary pathway of 23S rRNA 3' end maturation; Belongs to the YhaM family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. Plays a role in the secondary pathway of 23S rRNA 3' end maturation. | 0.921 |
yhaM | yprB | BSU09930 | BSU22210 | 3'-5' exonuclease; Shows a 3'-5' exoribonuclease activity as well as single- stranded DNA 3'-5'exonuclease activity. Plays a role in the secondary pathway of 23S rRNA 3' end maturation; Belongs to the YhaM family. | Putative nucleic acid binding enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.414 |
yheC | kapD | BSU09780 | BSU31470 | Spore coat associated protein, similar to YheD; Involved in sporulation; Belongs to the YheC/YheD family. | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | 0.643 |
yheC | yheD | BSU09780 | BSU09770 | Spore coat associated protein, similar to YheD; Involved in sporulation; Belongs to the YheC/YheD family. | Spore coat associated protein; Involved in sporulation. | 0.970 |
yheC | yueB | BSU09780 | BSU31860 | Spore coat associated protein, similar to YheD; Involved in sporulation; Belongs to the YheC/YheD family. | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | 0.415 |
yheD | kapD | BSU09770 | BSU31470 | Spore coat associated protein; Involved in sporulation. | Putative exoribonuclease (3'-5'); Specifically inhibits the KinA pathway to sporulation. | 0.469 |