Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nupPPermease of ABC guanosine transporter; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily. (348 aa)    
Predicted Functional Partners:
nupO
Guanosine ABC transporter (ATP-binding protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter; Belongs to the ABC transporter superfamily.
 
 0.999
nupQ
Permease of ABC guanosine transporter; Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrates across the membrane (By similarity).
 
0.999
nupN
Lipoprotein involved in guanosine transport; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein.
 
 
 0.995
nupC
Pyrimidine-nucleoside Na+(H+) cotransporter; Transport of the pyrimidine nucleoside uridine.
      
 0.879
med
Positive regulator of comK; Positive activator of the comK gene; Belongs to the BMP lipoprotein family.
 
   
 0.838
rbsA
Ribose ABC transporter (ATP-binding protein); Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
     0.721
dppB
Dipeptide ABC transporter (permease); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions.
   
    0.509
drm
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
    0.507
ymfC
Putative transcriptional regulator (GntR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
 
     0.491
dppC
Dipeptide ABC transporter (permease); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation.
   
    0.487
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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