| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| nrnB | yeeF | BSU18200 | BSU06812 | Oligoribonuclease (nanoRNase); Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines. | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | 0.575 |
| nrnB | yueB | BSU18200 | BSU31860 | Oligoribonuclease (nanoRNase); Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines. | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | 0.698 |
| nrnB | yukB | BSU18200 | BSU31875 | Oligoribonuclease (nanoRNase); Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines. | Putative cell division protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.637 |
| nrnB | yukC | BSU18200 | BSU31890 | Oligoribonuclease (nanoRNase); Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines. | Putative membrane-associated enzyme involved in bacteriocin production; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.668 |
| nrnB | yukE | BSU18200 | BSU31910 | Oligoribonuclease (nanoRNase); Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15576783. | 0.662 |
| ybgA | yueB | BSU02370 | BSU31860 | Putative transcriptional regulator (GntR family); Transcriptional repressor of genes involved in glucosamine transport and utilization. Represses the expression of the gamAP operon by binding to the gamA-gamR intergenic region. | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | 0.845 |
| yeeF | nrnB | BSU06812 | BSU18200 | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | Oligoribonuclease (nanoRNase); Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines. | 0.575 |
| yeeF | yueB | BSU06812 | BSU31860 | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | 0.715 |
| yeeF | yukB | BSU06812 | BSU31875 | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | Putative cell division protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.766 |
| yeeF | yukC | BSU06812 | BSU31890 | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | Putative membrane-associated enzyme involved in bacteriocin production; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.760 |
| yeeF | yukE | BSU06812 | BSU31910 | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15576783. | 0.831 |
| yhgE | yueB | BSU10160 | BSU31860 | Putative methyl-accepting protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | 0.643 |
| yhgE | yukC | BSU10160 | BSU31890 | Putative methyl-accepting protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Putative membrane-associated enzyme involved in bacteriocin production; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.435 |
| yhgE | yukE | BSU10160 | BSU31910 | Putative methyl-accepting protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15576783. | 0.457 |
| yueB | nrnB | BSU31860 | BSU18200 | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | Oligoribonuclease (nanoRNase); Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines. | 0.698 |
| yueB | ybgA | BSU31860 | BSU02370 | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | Putative transcriptional regulator (GntR family); Transcriptional repressor of genes involved in glucosamine transport and utilization. Represses the expression of the gamAP operon by binding to the gamA-gamR intergenic region. | 0.845 |
| yueB | yeeF | BSU31860 | BSU06812 | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | 0.715 |
| yueB | yhgE | BSU31860 | BSU10160 | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | Putative methyl-accepting protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.643 |
| yueB | yueC | BSU31860 | BSU31850 | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | Hypothetical protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.992 |
| yueB | yueD | BSU31860 | BSU31840 | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | Putative aromatic compound reductase; Reduces benzil stereospecifically to (S)-benzoin. | 0.976 |