| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| rtbD | yeeF | BSU39300 | BSU06812 | Ribonuclease toxin of the RtbD-RtbE toxin-antitoxin system; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 409-569) has RNase activity, and inhibits growth upon expression in E.coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD, but not by antitoxins specific to other toxins with the LXG domain. | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | 0.914 |
| rtbD | yueB | BSU39300 | BSU31860 | Ribonuclease toxin of the RtbD-RtbE toxin-antitoxin system; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 409-569) has RNase activity, and inhibits growth upon expression in E.coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD, but not by antitoxins specific to other toxins with the LXG domain. | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | 0.472 |
| rtbD | yukB | BSU39300 | BSU31875 | Ribonuclease toxin of the RtbD-RtbE toxin-antitoxin system; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 409-569) has RNase activity, and inhibits growth upon expression in E.coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD, but not by antitoxins specific to other toxins with the LXG domain. | Putative cell division protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.524 |
| rtbD | yukC | BSU39300 | BSU31890 | Ribonuclease toxin of the RtbD-RtbE toxin-antitoxin system; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 409-569) has RNase activity, and inhibits growth upon expression in E.coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD, but not by antitoxins specific to other toxins with the LXG domain. | Putative membrane-associated enzyme involved in bacteriocin production; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.853 |
| rtbD | yukD | BSU39300 | BSU31900 | Ribonuclease toxin of the RtbD-RtbE toxin-antitoxin system; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 409-569) has RNase activity, and inhibits growth upon expression in E.coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD, but not by antitoxins specific to other toxins with the LXG domain. | Putative bacteriocin; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Belongs to the EsaB family. | 0.727 |
| rtbD | yukE | BSU39300 | BSU31910 | Ribonuclease toxin of the RtbD-RtbE toxin-antitoxin system; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 409-569) has RNase activity, and inhibits growth upon expression in E.coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD, but not by antitoxins specific to other toxins with the LXG domain. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15576783. | 0.798 |
| spoIIIE | yfjA | BSU16800 | BSU08170 | Spore DNA translocase; Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation, for the final steps of compartmentalization in the presence of trapped DNA, and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA i [...] | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the WXG100 family. | 0.616 |
| spoIIIE | yueB | BSU16800 | BSU31860 | Spore DNA translocase; Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation, for the final steps of compartmentalization in the presence of trapped DNA, and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA i [...] | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | 0.644 |
| spoIIIE | yueC | BSU16800 | BSU31850 | Spore DNA translocase; Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation, for the final steps of compartmentalization in the presence of trapped DNA, and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA i [...] | Hypothetical protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.483 |
| spoIIIE | yukC | BSU16800 | BSU31890 | Spore DNA translocase; Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation, for the final steps of compartmentalization in the presence of trapped DNA, and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA i [...] | Putative membrane-associated enzyme involved in bacteriocin production; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.658 |
| spoIIIE | yukD | BSU16800 | BSU31900 | Spore DNA translocase; Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation, for the final steps of compartmentalization in the presence of trapped DNA, and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA i [...] | Putative bacteriocin; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Belongs to the EsaB family. | 0.758 |
| spoIIIE | yukE | BSU16800 | BSU31910 | Spore DNA translocase; Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation, for the final steps of compartmentalization in the presence of trapped DNA, and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA i [...] | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15576783. | 0.861 |
| yeeF | rtbD | BSU06812 | BSU39300 | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | Ribonuclease toxin of the RtbD-RtbE toxin-antitoxin system; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 409-569) has RNase activity, and inhibits growth upon expression in E.coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YxxD, but not by antitoxins specific to other toxins with the LXG domain. | 0.914 |
| yeeF | yueB | BSU06812 | BSU31860 | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | 0.719 |
| yeeF | yukB | BSU06812 | BSU31875 | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | Putative cell division protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.773 |
| yeeF | yukC | BSU06812 | BSU31890 | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | Putative membrane-associated enzyme involved in bacteriocin production; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.907 |
| yeeF | yukE | BSU06812 | BSU31910 | Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable). | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15576783. | 0.918 |
| yfjA | spoIIIE | BSU08170 | BSU16800 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the WXG100 family. | Spore DNA translocase; Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation, for the final steps of compartmentalization in the presence of trapped DNA, and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA i [...] | 0.616 |
| yfjA | yueB | BSU08170 | BSU31860 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the WXG100 family. | Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage. | 0.565 |
| yfjA | yueC | BSU08170 | BSU31850 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the WXG100 family. | Hypothetical protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). | 0.747 |
