STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metQMethionine ABC transporter, substrate binding lipoprotein; Part of the ABC transporter complex MetNPQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable); Belongs to the NlpA lipoprotein family. (274 aa)    
Predicted Functional Partners:
metP
Methionine ABC transporter, permease component; Part of the ABC transporter complex MetNPQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 0.999
metN
Methionine ABC transporter (ATP-binding protein); Part of the ABC transporter complex MetNPQ involved in methionine import. Responsible for energy coupling to the transport system (Probable). It has also been shown to be involved in methionine sulfoxide transport. Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
 0.999
yhcJ
Putative ABC transporter (binding lipoprotein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
  
 
 
0.930
glnH
Glutamine ABC transporter (glutamine-binding lipoprotein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport; Belongs to the bacterial solute-binding protein 3 family.
 
  
 0.817
samT
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.683
glcU
Glucose uptake protein; Involved in the uptake of glucose.
      
 0.677
pstS
Phosphate ABC transporter (binding lipoprotein); Part of the ABC transporter complex PstSACB involved in phosphate import.
      
 0.619
yurZ
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
       0.570
cotU
Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
      
 0.483
yqfQ
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.483
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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