node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
amyE | bpr | BSU03040 | BSU15300 | Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family. | Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | 0.523 |
amyE | cssR | BSU03040 | BSU33010 | Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family. | Two-component response regulator; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. | 0.484 |
amyE | cssS | BSU03040 | BSU33020 | Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family. | Two-component sensor histidine kinase; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htrA. Could detect misfolded proteins at the membrane-cell wall interface and then activate CssR by phosphorylation. | 0.494 |
amyE | htrA | BSU03040 | BSU12900 | Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family. | Membrane bound serine protease Do, quality control protease (heat-shock protein); Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (Probable); Belongs to the peptidase S1C family. | 0.532 |
amyE | htrB | BSU03040 | BSU33000 | Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family. | HtrA-like serine protease; Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (Probable); Belongs to the peptidase S1C family. | 0.709 |
amyE | nprE | BSU03040 | BSU14700 | Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family. | Extracellular neutral metalloprotease; Extracellular zinc metalloprotease; Belongs to the peptidase M4 family. | 0.769 |
amyE | prsA | BSU03040 | BSU09950 | Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family. | Molecular chaperone lipoprotein; Essential protein that plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. Has PPIase activity but it is not essential for its function in vivo; Belongs to the PrsA family. | 0.590 |
amyE | wprA | BSU03040 | BSU10770 | Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family. | Cell wall-associated protease; CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges; Belongs to the peptidase S8 family. | 0.685 |
bpr | amyE | BSU15300 | BSU03040 | Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family. | 0.523 |
bpr | htrA | BSU15300 | BSU12900 | Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | Membrane bound serine protease Do, quality control protease (heat-shock protein); Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (Probable); Belongs to the peptidase S1C family. | 0.504 |
bpr | htrB | BSU15300 | BSU33000 | Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | HtrA-like serine protease; Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (Probable); Belongs to the peptidase S1C family. | 0.693 |
bpr | nprE | BSU15300 | BSU14700 | Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | Extracellular neutral metalloprotease; Extracellular zinc metalloprotease; Belongs to the peptidase M4 family. | 0.935 |
bpr | prsA | BSU15300 | BSU09950 | Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | Molecular chaperone lipoprotein; Essential protein that plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. Has PPIase activity but it is not essential for its function in vivo; Belongs to the PrsA family. | 0.417 |
bpr | wprA | BSU15300 | BSU10770 | Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | Cell wall-associated protease; CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges; Belongs to the peptidase S8 family. | 0.523 |
cssR | amyE | BSU33010 | BSU03040 | Two-component response regulator; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. | Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family. | 0.484 |
cssR | cssS | BSU33010 | BSU33020 | Two-component response regulator; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. | Two-component sensor histidine kinase; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htrA. Could detect misfolded proteins at the membrane-cell wall interface and then activate CssR by phosphorylation. | 0.999 |
cssR | htrA | BSU33010 | BSU12900 | Two-component response regulator; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. | Membrane bound serine protease Do, quality control protease (heat-shock protein); Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (Probable); Belongs to the peptidase S1C family. | 0.967 |
cssR | htrB | BSU33010 | BSU33000 | Two-component response regulator; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. | HtrA-like serine protease; Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (Probable); Belongs to the peptidase S1C family. | 0.983 |
cssR | prsA | BSU33010 | BSU09950 | Two-component response regulator; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. | Molecular chaperone lipoprotein; Essential protein that plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. Has PPIase activity but it is not essential for its function in vivo; Belongs to the PrsA family. | 0.602 |
cssR | wprA | BSU33010 | BSU10770 | Two-component response regulator; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. | Cell wall-associated protease; CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges; Belongs to the peptidase S8 family. | 0.496 |