Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yvrBPutative vitamin B12 permease; Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane (By similarity). (353 aa)    
Predicted Functional Partners:
yvrC
Putative lipoprotein binding vitamin B12; Probably part of an ABC transporter complex.
 
 
 0.992
yvrA
Putative vitamin B12 transport system, ATPase component; Probably part of an ABC transporter complex. Probably responsible for energy coupling to the transport system (By similarity).
 
 0.979
fhuC
Ferrichrome ABC transporter (ATP-binding protein); Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system (By similarity); Belongs to the ABC transporter superfamily. Iron (Fe3+)- hydroxamate importer (TC 3.A.1.14.7) family.
 
 0.912
yusV
iron(III)-siderophore transporter (ATP binding component); Provides the ATPase subunit for at least 2 ABC transporter complexes; YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable), and FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable). Probably responsible for energy coupling to the transport system (By similarity).
 
 0.907
yfmF
Iron-dicitrate ABC transporter (ATP-binding protein); Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Responsible for energy coupling to the transport system (Probable).
 
 0.902
pduO
Putative ATP:cob(I)alamin adenosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e: enzyme.
  
  
 0.817
ykuO
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12354229.
   
    0.807
yfmC
Iron-dicitrate ABC transporter (binding lipoprotein); Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of YfmDE (Probable). Belongs to the bacterial solute-binding protein 8 family.
 
  
 0.493
yfiZ
iron(III) siderophore transport permease; Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen.
 
   
0.479
yfmD
Iron-dicitrate ABC transporter (permease); Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable).
 
   
0.475
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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