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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yvbFPutative transcriptional regulator; Negatively regulates the transcription of the opuC operon. In the absence of GbsR, is also a negative regulator of the opuB operon. Binds to an inverted repeat in the promoter region of the operons. (185 aa)    
Predicted Functional Partners:
opuCA
Glycine betaine/carnitine/choline/choline sulfate ABC transporter (ATP-binding protein); Involved in a high affinity multicomponent binding-protein- dependent transport system for glycine betaine, carnitine and choline; probably responsible for energy coupling to the transport system.
  
  
 0.812
opuBD
Choline ABC transporter (permease); Involved in a high affinity multicomponent binding-protein- dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane.
  
  
 0.808
opuBA
Choline ABC transporter (ATP-binding protein); Involved in a high affinity multicomponent binding-protein- dependent transport system for choline. Probably responsible for energy coupling to the transport system.
  
  
 0.794
opuCB
Glycine betaine/carnitine/choline/choline sulfate ABC transporter (permease); Involved in a high affinity multicomponent binding-protein- dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
  
  
 0.723
opuBC
Choline ABC transporter (choline-binding lipoprotein); Member of a high affinity multicomponent binding-protein- dependent transport system for choline.
  
  
 0.705
opuCD
Glycine betaine/carnitine/choline/choline sulfate ABC transporter (permease); Involved in a high affinity multicomponent binding-protein- dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
  
  
 0.636
opuE
Proline transporter; Catalyzes the uptake of extracellular proline under high- osmolarity growth conditions. Essential for the use of proline present in the environment as an osmoprotectant.
   
  
 0.625
opuCC
Glycine betaine/carnitine/choline-binding protein OpuCC; Member of a high affinity multicomponent binding-protein- dependent transport system for glycine betaine, carnitine, and choline. Belongs to the OsmX family.
  
  
 0.589
opuAA
Glycine betaine ABC transporter (ATP-binding protein); Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. Probably responsible for energy coupling to the transport system.
 
  
 0.571
gbsB
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine from choline; Belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.571
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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